News tagged with drug concentrations
'Type case' makes sparing use of laboratory animals
Researchers at the University of Twente's MIRA research institute have developed a system which may drastically reduce the use of laboratory animals in science. The system, which is designed to be implanted in laboratory ...
Other
May 16, 2013 |
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Malaria parasite protein identified as potential new target for drug treatment
Scientists have discovered how a protein within the malaria parasite is essential to its survival as it develops inside a mosquito. They believe their findings identify this protein as a potential new target for drug treatments ...
Medical research
Apr 25, 2013 |
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Treatment for novel coronavirus shows promise in early lab tests
National Institutes of Health (NIH) scientists studying an emerging coronavirus have found that a combination of two licensed antiviral drugs, ribavirin and interferon-alpha 2b, can stop the virus from replicating ...
Diseases, Conditions, Syndromes
Apr 18, 2013 |
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Tenofovir Gel wins out in drug absorption study, but HIV prevention trials say differently
A novel head-to-head study looking at differences in how the antiretroviral (ARV) drug tenofovir gets absorbed in the body as either an oral tablet or a vaginal gel found tenofovir gel can achieve substantially higher concentrations ...
HIV & AIDS
Jan 30, 2013 |
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New study finds key mechanism in calcium regulation
All living cells keep their cellular calcium concentration at a very low level. Since a small increase in calcium can affect many critical cellular functions (an elevated calcium concentration over an extended period can ...
Neuroscience
Jan 03, 2013 |
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Innovative method to deliver THC: Transmucosal patch increases drug's absorption
(Medical Xpress)—An innovative delivery method for tetrahydrocannabinol, the main psychoactive constituent of Cannabis, is being developed at the University of Mississippi.
Medications
Dec 20, 2012 |
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FDA pulls one generic form of wellbutrin off the market
(HealthDay)—People taking the antidepressant Wellbutrin now have one less option for a generic version of the drug.
Medications
Dec 06, 2012 |
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'Repurposed' anti-parasite drug shows promise as new TB treatment
(Medical Xpress)—A well-established family of drugs used to treat parasitic diseases is showing surprising potential as a therapy for tuberculosis (TB), according to new research from University of British Columbia microbiologists.
Diseases, Conditions, Syndromes
Nov 23, 2012 |
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Genetically-engineered preclinical models predict pharmacodynamic response
New cancer drugs must be thoroughly tested in preclinical models, often in mice, before they can be offered to cancer patients for the first time in phase I clinical trials. Key components of this process include pharmacokinetic ...
Cancer
Sep 19, 2012 |
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NIH-funded analysis estimates effective PrEP dosing
Several large clinical trials have demonstrated that a daily oral dose of one or two antiretroviral drugs used to treat HIV infection can prevent infection in an approach known as pre-exposure prophylaxis, or PrEP. The level ...
HIV & AIDS
Sep 13, 2012 |
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Research underscores Truvada's potency in preventing the transmission of HIV
New research from an international team of HIV/AIDS experts has reaffirmed the effectiveness of Truvada—the first and only medication approved by the FDA for HIV prevention. Led by Gladstone Investigator Robert Grant, MD, ...
HIV & AIDS
Sep 12, 2012 |
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First targeted nanomedicine to enter human clinical studies
A team of scientists, engineers and physicians from Brigham and Women's Hospital (BWH), Dana-Farber Cancer Institute (DFCI), Harvard Medical School (HMS), Massachusetts Institute of Technology (MIT), BIND ...
Cancer
Apr 04, 2012 |
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BIND presents late-breaker clinical data at AACR on BIND-014's promising antitumor effects
BIND Biosciences, a clinical-stage biopharmaceutical company developing a new class of highly selective targeted therapeutics called AccurinsTM, announced today the presentation of late-breaker clinical data for BIND-014, ...
Cancer
Apr 04, 2012 |
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Smart contact lenses could make eye drops a thing of the past
(Medical Xpress) -- An Auburn University team of chemical and biomedical engineers led by Mark Byrne, the Daniel F. and Josephine Breeden Associate Professor in the Samuel Ginn College of Engineering, has developed a new ...
Medical research
Nov 09, 2011 |
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Through-the-nipple breast cancer therapy shows promise in early tests
Delivering anticancer drugs into breast ducts via the nipple is highly effective in animal models of early breast cancer, and has no major side effects in human patients, according to a report by Johns Hopkins Kimmel Cancer ...
Cancer
Oct 26, 2011 |
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