News tagged with drug development


Chloroquine makes comeback to combat malaria

Malaria-drug monitoring over the past 30 years has shown that malaria parasites develop resistance to medicine, and the first signs of resistance to the newest drugs have just been observed. At the same time, resistance monitoring ...

Diseases, Conditions, Syndromes created Oct 03, 2012 | popularity not rated yet | comments 0

Fluoxetine increases aggressive behavior, affects brain development among adolescent hamsters

Fluoxetine was the first drug approved by the FDA for major depressive disorder (MDD) in children and adolescents, and to this date, it remains one of only two selective serotonin reuptake inhibitors (SSRIs) registered for ...

Psychology & Psychiatry created Oct 01, 2012 | popularity 5 / 5 (1) | comments 0

Promising compound selected as drug candidate for tuberculosis

(Medical Xpress)—A New Zealand-designed compound that shows promise against treatment-resistance tuberculosis (TB) has been selected as a drug candidate by international non-profit drug developer the Global Alliance for ...

Diseases, Conditions, Syndromes created Sep 17, 2012 | popularity not rated yet | comments 0

Aubagio approved for multiple sclerosis

(HealthDay)—Aubagio (teriflunomide) has been approved by the U.S. Food and Drug Administration to treat adults with relapsing forms of multiple sclerosis (MS).

Medications created Sep 13, 2012 | popularity not rated yet | comments 0

Cell death mystery yields new suspect for cancer drug development

A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.

Cancer created Sep 13, 2012 | popularity 5 / 5 (3) | comments 0

Do it like the immune system: novel antimicrobials

Microbial infections are becoming unbeatable due to progressive mutations that lead to antimicrobial drug resistance. European scientists exploited the characteristics of novel antimicrobial compounds that ...

Medications created Aug 30, 2012 | popularity not rated yet | comments 0

New technology combats global pandemic of drug counterfeiting

Drug counterfeiting is so common in some developing countries that patients with serious diseases in Southeast Asia and elsewhere are at risk of getting a poor-quality drug instead of one with ingredients that really treat ...

Medications created Aug 19, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

'CYCLOPS' genes may serve as an Achilles' heel in tumor cells

BOSTON--The genomic tumult within tumor cells has provided scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard with clues to an entirely new class of genes that may serve as an Achilles' ...

Genetics created Aug 15, 2012 | popularity not rated yet | comments 0 | with audio podcast

Breastfeeding may protect infants from HIV transmission

An international team of researchers has found that certain bioactive components found in human milk are associated with a reduced risk of HIV transmission from an HIV infected mother to her breast-fed infant. Their study ...

HIV & AIDS created Aug 15, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Protein that helps tumor blood vessels mature could make cancer drugs more effective

Since anti-cancer drugs are carried to tumors by the bloodstream, abnormal blood vessel development can hamper delivery. In a paper published Aug. 14 in Cancer Cell, researchers at Sanford-Burnham Medica ...

Cancer created Aug 13, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Lower risk of serious side-effects in trials of new targeted drugs

Patients in early clinical trials of new-style targeted cancer therapies appear to have a much lower risk of the most serious side-effects than with traditional chemotherapy, according to a new analysis.

Cancer created Aug 07, 2012 | popularity not rated yet | comments 0

Researchers look at the spread of dysentery from Europe to industrializing countries

Researchers have found that a bacterium that emerged centuries ago in Europe has now been spreading globally into countries undergoing rapid development and industrialization. Unlike other diarrheal diseases, this one is ...

Genetics created Aug 05, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists: Novel TB drug combo passes first test

Scientists are hot on the trail of a new tuberculosis treatment that a small study suggests might one day offer an alternative to battle this deadly lung disease, even if it is resistant to today's two main drugs.

Diseases, Conditions, Syndromes created Jul 23, 2012 | popularity not rated yet | comments 0

Predicting toxicity in the drug development pipeline

University College Dublin researchers have reported in Molecular & Cellular Proteomics on a proof-of-principle study that may benefit the pharmaceutical industry in the future by providing a roadmap for la ...

Medical research created Jul 19, 2012 | popularity not rated yet | comments 0

HIV drug resistance creeps higher: WHO

Drug resistance to HIV medicines has been creeping higher in parts of Africa and Asia but is not steep enough to cause alarm, said a survey released by the World Health Organization on Wednesday.

HIV & AIDS created Jul 18, 2012 | popularity not rated yet | comments 0