News tagged with drug development
Scientists develop mouse model that could lead to new therapies for liver cancer
Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step ...
Cancer
Jul 06, 2012 |
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Merck KGaA suffers setback on cancer drug
German pharmaceuticals maker Merck KGaA said Thursday that phase III clinical trials of its gastric cancer drug Erbitux had shown no benefits for patients.
Cancer
Jul 05, 2012 |
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New drug prospect offers hope against hookworm infections
A drug candidate that is nearing clinical trials against a Latin American parasite is showing additional promise as a cure for hookworm, one of the most widespread and insidious parasites afflicting developing nations, according ...
Diseases, Conditions, Syndromes
Jul 03, 2012 |
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In vitro study identifies potential combination therapy for breast cancer
A study conducted at Boston University School of Medicine (BUSM) demonstrates an effective combination therapy for breast cancer cells in vitro. The findings, published in the July 2012 issue of Anticancer Research, raise ...
Cancer
Jul 02, 2012 |
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Hong Kong's first anti-cancer drug granted with US FDA IND
(Medical Xpress) -- The discovery of a new drug for liver cancer by researchers of The Hong Kong Polytechnic University (PolyU) and local medical practitioner has born fruit. After completing clinical trials locally, the ...
Cancer
Jun 29, 2012 |
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South African daffodils may be a future cure for depression
Scientists at the University of Copenhagen have previously documented that substances from the South African plant species Crinum and Cyrtanthus – akin to snowdrops and daffodils – have an effect ...
Medications
Jun 22, 2012 |
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The challenges and opportunities of clinical trials in developing countries
Conducting more clinical trials in developing countries is of benefit because these populations are underrepresented in research, but doing trials in resource poor settings has many challenges. Research sites in developing ...
Other
Jun 12, 2012 |
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Growing presence of drug-resistant tuberculosis fuels need for faster development of new combination therapies
Johns Hopkins experts in the prevention and treatment of multidrug-resistant tuberculosis are calling for increased screening and more rapid testing of the 9 million people worldwide estimated to be infected each year with ...
Diseases, Conditions, Syndromes
Jun 06, 2012 |
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China faces 'serious' epidemic of drug-resistant TB (Update)
China faces a "serious epidemic" of drug-resistant tuberculosis according to the first-ever nationwide estimate of the size of the problem there, said a US-published study on Wednesday.
Diseases, Conditions, Syndromes
Jun 06, 2012 |
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Cancer drugs: better, cheaper
Cancer drug development is known to be too slow, costly and fraught with failure. Now the U.S. Food and Drug Administration is issuing recommendations for breast cancer trials that would substantially accelerate patient access ...
Cancer
Jun 04, 2012 |
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Simple cooler preserves tuberculosis drugs, records doses
Tuberculosis, now largely controlled in the industrialized world, remains a stubbornly persistent killer in most of Africa, as well as parts of Asia and South America. The spread of multidrug-resistant strains of TB has slowed ...
Medical research
May 30, 2012 |
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Elimination of two ribosome subunits activates cell cycle control
Alterations in the formation of ribosomes (the elements of the cell where proteins are made) cause the induction of p53 protein and cell cycle disruption. This process is crucial to understand fundamental biological processes ...
Genetics
May 22, 2012 |
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Study raises questions about use of anti-epilepsy drugs in newborns
A brain study in infant rats demonstrates that the anti-epilepsy drug phenobarbital stunts neuronal growth, which could prompt new questions about using the first-line drug to treat epilepsy in human newborns.
Neuroscience
May 11, 2012 |
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Key protein's newly discovered form and function may provide novel cancer treatment target
Research led by St. Jude Children's Research Hospital investigators suggests that safeguarding cell survival and maintaining a balanced immune system is just the start of the myeloid cell leukemia sequence 1 (MCL1) protein's ...
Cancer
Apr 30, 2012 |
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Not enough is known about prescription drug use in pregnancy, say experts
Prescription drug use during pregnancy is prevalent, however, not enough is known about the adverse effects they may have on the developing fetus, concludes a new review published in The Obstetrician & Gynaecologist (TOG) ...
Obstetrics & gynaecology
Apr 27, 2012 |
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