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GSK buys asthma drug developer for up to $1.4 bn
British drugmaker GlaxoSmithKline on Tuesday agreed to buy Aiolos Bio for up to $1.4 billion, with focus on an asthma medication still at the testing stage.
Jan 9, 2024
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News tagged with drug development
Genetics
Novel genetic priority score unveiled to enhance target prioritization in drug development
Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types ...
Jan 3, 2024
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Genetics
Multi-ancestry study uncovers shared genetics of problematic drinking
A study led by VA Connecticut Healthcare Center/Yale researchers reveals ancestries around the world possess a shared genetic architecture for problematic alcohol use (PAU)—habitual heavy drinking, accompanied by harmful ...
Dec 22, 2023
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Medical research
Q&A: Behind the approvals—decades of research lead to a new generation of targeted cancer therapies
Last month, the U.S. Food and Drug Administration (FDA) approved the use of the drug capivasertib, in combination with a current cancer treatment called fulvestrant for patients with the most common type of breast cancer, ...
Dec 21, 2023
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Diseases, Conditions, Syndromes
A new weapon against the super-tough C diff bacteria tested in phase-one human trial
In a phase-one human clinical trial, a University of Houston pharmacist researcher has demonstrated that a newer generation tetracycline antibiotic, called Omadacycline, may be a promising tool in combating the resilient ...
Dec 19, 2023
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Oncology & Cancer
Secret vulnerabilities of cancer's 'Death Star' protein revealed
Researchers at the Center for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS. These are ...
Dec 18, 2023
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Medical research
CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?
Prescription drugs and vaccines revolutionized health care, dramatically decreasing death from disease and improving quality of life across the globe. But how do researchers, universities and hospitals, and the pharmaceutical ...
Dec 14, 2023
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Oncology & Cancer
Researchers develop 'potent and specific' compounds to curb cancer growth
Proteasomes are protein-degrading complexes that are important for cancer cell survival. Proteasome inhibitors are commonly used to treat diseases such as multiple myeloma and mantle cell lymphoma. Proteasomes have three ...
Dec 14, 2023
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Medical research
Psychedelic drugs: Follow the money as investors seek to replace Prozac, Zoloft and other drugs
The golden road to pharmaceutical riches can quickly become a rocky wilderness trail. Chemical compounds that hit a target in the lab often fall short in human studies.
Dec 13, 2023
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Medications
Why you might not find your favorite cold meds at the pharmacy
It's winter and many people are contending with the sniffles and coughs. For some, that means heading to the pharmacy to resupply on cold medications.
Dec 11, 2023
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