Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks of DNA molecules—cells ...
Apr 4, 2013
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Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...
Aug 14, 2019
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A four-drug chemotherapy regimen provided longer overall survival than a two-drug combination in a Phase 3 clinical trial for metastatic pancreatic ductal adenocarcinoma. The study is believed to be the first metastatic pancreatic ...
Jan 20, 2023
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Scientists at Scripps Research, Florida have determined the near-atomic-scale structure of an unusual brain-cell receptor called GPR158, which has been linked to depression and anxiety.
Nov 18, 2021
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Pfizer is spending $11.6 billion to buy the remaining portion of migraine treatment maker Biohaven Pharmaceuticals it does not already own.
May 10, 2022
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A combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we have entered a new era of drug development that will deliver them. In an editorial published in the Journal ...
Jul 6, 2022
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An extensive international study led by Prof. Illana Gozes of Tel Aviv University's Department of Human Molecular Genetics and Biochemistry found deposits of the tau protein typically found in Alzheimer's patients in tissues ...
Jul 28, 2020
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The most comprehensive genome-wide association study, or GWAS, of colorectal cancer risk to date, published today in Nature Genetics, has discovered 40 new genetic variants and validated 55 previously identified variants ...
Dec 3, 2018
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Flavored oral nicotine products, which contain no tobacco but are not FDA-approved to help people quit smoking, are increasingly marketed and sold in the U.S., but researchers have never measured their use among U.S. teens.
Aug 8, 2022
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Parkinson's Disease develops if a certain anti-viral receptor and its protein in the brain, called the interferon-beta pathway, is not functioning correctly. That causes the pathway to be blocked, and as a result the brain ...
Oct 8, 2021
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