New drug shows promise in ability to fight rare type of breast cancer
Researchers in the University of Delaware's Department of Biological Sciences are investigating a new drug that has shown positive results in early tests of its ability to fight a rare and aggressive form ...
Cancer
Mar 08, 2013 |
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Novel small molecules used to visualize prostate cancer
Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published ...
Cancer
Mar 05, 2013 |
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First-in-man study demonstrates the therapeutic effect of RNAi gene silencing in cancer treatment
A study led by Dr Josep Tabernero, the Director of Clinical Research at the Vall d'Hebron Institute of Oncology (VHIO) and Head of the Medical Oncology Department at the Vall d'Hebron University Hospital, shows for the first ...
Cancer
Feb 11, 2013 |
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For drug makers, new 3-D control opens wealth of options
A team of scientists anchored at Yale University has demonstrated a new, highly versatile approach for quickly assembling drug-like compounds, establishing a broad new route to drug discovery and medical treatment. They report ...
Medications
Feb 07, 2013 |
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Novel technique reveals dynamics of telomere DNA structure
Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural ...
Medical research
Jan 17, 2013 |
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Discovery promises to improve drugs used to fight cancer, other diseases
(Medical Xpress)—Even when at rest, the human body is a flurry of activity. Like a microscopic metropolis locked in a state of perpetual rush hour traffic, the trillions of cells that make us who we are work feverishly ...
Medical research
Jan 11, 2013 |
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Targeted gene silencing drugs are more than 500 times more effective with new delivery method
Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically ...
Medical research
Dec 21, 2012 |
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Automated design for drug discovery
A system of 'automated design' for new drugs could help develop the complex therapies needed for many medical conditions while also improving drug safety and efficiency, new research from the University of Dundee has shown.
Medications
Dec 12, 2012 |
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Abnormal DNA maintenance related to cancer
DNA, like houses and cars, needs ongoing maintenance. Rays of ultraviolet sunlight, chemical pollutants and normal biochemical processes in the cell can damage it. Cells routinely repair this damage before making proteins ...
Cancer
Dec 10, 2012 |
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New small molecule inhibitor could be a safe and first-line treatment for metastatic breast cancer
Previous research has shown that a family of genes, proteins and enzymes called the uPA system (for urokinase plasminogen activator) plays an active role in different facets of cancer's biology, including tumor cell invasion, ...
Cancer
Dec 08, 2012 |
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Cell surface transporters exploited for cancer drug delivery
Whitehead Institute scientists report that certain molecules present in high concentrations on the surfaces of many cancer cells could be exploited to funnel lethal toxic molecules into the malignant cells. In such an approach, ...
Genetics
Dec 02, 2012 |
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Proteins that work at the ends of DNA could provide cancer insight
(Medical Xpress)—New insights into a protein complex that regulates the very tips of chromosomes could improve methods of screening anti-cancer drugs.
Medical research
Nov 29, 2012 |
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Scientists identify potential drug target for inflammatory diseases including cancers
A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune ...
Inflammatory disorders
Nov 21, 2012 |
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Discovery of molecular pathway of Alzheimer's disease reveals new drug targets
The discovery of the molecular pathway that drives the changes seen in the brains of Alzheimer's patients is reported today, revealing new targets for drug discovery that could be exploited to combat the disease. The study ...
Alzheimer's disease & dementia
Nov 20, 2012 |
4.5 / 5 (2) |
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Meth vaccine shows promising results in early tests
Scientists at The Scripps Research Institute (TSRI) have performed successful tests of an experimental methamphetamine vaccine on rats. Vaccinated animals that received the drug were largely protected from ...
Psychology & Psychiatry
Nov 01, 2012 |
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