Discovery could reduce chemotherapy's side effects
A team of researchers at Duke University has determined the structure of a key molecule that can carry chemotherapy and anti-viral drugs into cells, which could help to create more effective drugs with fewer effects to healthy ...
Cancer
Mar 11, 2012 |
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Molecule's role in cancer suggests new combination therapy
Researchers at the University of Illinois at Chicago College of Medicine have found that a molecule found at elevated levels in cancer cells seems to protect them from the "cell-suicide" that is usually triggered by chemotherapy ...
Cancer
Mar 01, 2012 |
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Comparing antimalarial drugs and their effects over the Plasmodium lifecycle
In this week's PLoS Medicine, Michael Delves of Imperial College London, UK and colleagues compare the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human ...
Diseases, Conditions, Syndromes
Feb 21, 2012 |
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Researchers pave the way for improving treatment for Type 2 diabetes
In a study published last week in the prestigious Proceedings of the National Academy of Sciences of the United States of America, a team led by Dr. Vincent Poitout of the University of Montreal Hospital Research Centre (CRCHU ...
Diabetes
Feb 07, 2012 |
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A step closer to understanding, averting drug resistance
(Medical Xpress) -- The multidrug transporter EmrE functions as an asymmetric antiparallel dimer (molecule with two subunits). Drug (blue) transport from the inside to the outside of the cell membrane is accomplished ...
Medical research
Jan 31, 2012 |
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New synthetic molecules treat autoimmune disease in mice
A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists ...
Immunology
Dec 25, 2011 |
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Researchers use new finding to clear bloodstream malaria infection in mice
University of Iowa researchers and colleagues have discovered how malaria manipulates the immune system to allow the parasite to persist in the bloodstream. By rescuing this immune system pathway, the research team was able ...
Medical research
Dec 12, 2011 |
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Novel export-inhibitor shows promise for treating chronic lymphocytic leukemia
An experimental drug that works by blocking the export of key control molecules from the nucleus of cancer cells shows promise as a treatment for chronic lymphocytic leukemia (CLL) and other incurable B-cell malignancies, ...
Cancer
Dec 12, 2011 |
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Turning the spotlight on drug-resistant tumors
Molecular probes that can illuminate cancer cells are often invaluable tools in the fight against the disease. The latest addition to this group is a family of fluorescent probes that can highlight a particularly ...
Cancer
Dec 09, 2011 |
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A mother's touch may protect against drug cravings later
An attentive, nurturing mother may be able to help her children better resist the temptations of drug use later in life, according to a study in rats conducted by Duke University and the University of Adelaide in Australia.
Neuroscience
Dec 06, 2011 |
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Substance interfering with the cells handling of protein waste could become new cancer drug
(Medical Xpress) -- Researchers at Karolinska Institutet have identified a new kind of cancer drug that has been shown to be effective against tumours in different experimental systems. An article published in Nature Medicine shows ...
Cancer
Nov 07, 2011 |
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Study examines nicotine as a gateway drug
A landmark study in mice identifies a biological mechanism that could help explain how tobacco products could act as gateway drugs, increasing a person's future likelihood of abusing cocaine and perhaps other drugs as well, ...
Medical research
Nov 02, 2011 |
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Scientists design experimental treatment for iron-overload diseases
Iron overload is a common condition affecting millions of people worldwide. Excess iron in the body is toxic, and deposits can cause damage to the liver, heart and other organs. Current treatments, researchers ...
Medical research
Nov 01, 2011 |
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Medical researchers ID potential new drug target that could stop debilitating effects of MS
Medical researchers at the University of Alberta have discovered a potential new drug target for Multiple Sclerosis that could prevent physical disability associated with the disease, once a new drug is developed.
Medical research
Oct 26, 2011 |
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Enzymes possible targets for new anti-malaria drugs
Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes ...
Medical research
Sep 21, 2011 |
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