Making a window for drug delivery in the blood-brain barrier
(Medical Xpress)—The blood-brain barrier (BBB) prevents most large or hydrophilic (polar) molecules from getting into the brain. For many neurological diseases, like Parkinson's, the presence of the BBB ...
Medical research
Apr 30, 2013 |
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Heroin vaccine blocks relapse in preclinical study
Scientists at The Scripps Research Institute (TSRI) have reported successful preclinical tests of a new vaccine against heroin. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, preventing ...
Medical research
May 06, 2013 |
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New synthetic molecules treat autoimmune disease in mice
A team of Weizmann Institute scientists has turned the tables on an autoimmune disease. In such diseases, including Crohn's and rheumatoid arthritis, the immune system mistakenly attacks the body's tissues. But the scientists ...
Immunology
Dec 25, 2011 |
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Key pathway to stop dangerous, out-of-control inflammation discovered
A potential new strategy to developing new drugs to control inflammation without serious side effects has been found by Georgia State University researchers and international colleagues.
Inflammatory disorders
Apr 09, 2013 |
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Meth vaccine shows promising results in early tests
Scientists at The Scripps Research Institute (TSRI) have performed successful tests of an experimental methamphetamine vaccine on rats. Vaccinated animals that received the drug were largely protected from ...
Psychology & Psychiatry
Nov 01, 2012 |
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New discovery could lead to powerful new anti-malaria drugs
An international study has discovered a molecule which could form the basis of powerful new anti-malaria drugs. The paper "Quinolone-3-Diarylethers: a new class of drugs for a new era of malaria eradication" has been published ...
Medical research
Mar 20, 2013 |
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Will cell therapy become a 'third pillar' of medicine?
Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers. They outlined ...
Medical research
Apr 03, 2013 |
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Discovery promises to improve drugs used to fight cancer, other diseases
(Medical Xpress)—Even when at rest, the human body is a flurry of activity. Like a microscopic metropolis locked in a state of perpetual rush hour traffic, the trillions of cells that make us who we are work feverishly ...
Medical research
Jan 11, 2013 |
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For drug makers, new 3-D control opens wealth of options
A team of scientists anchored at Yale University has demonstrated a new, highly versatile approach for quickly assembling drug-like compounds, establishing a broad new route to drug discovery and medical treatment. They report ...
Medications
Feb 07, 2013 |
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Discovery could help combat chronic pain in diabetics
(Medical Xpress) -- Researchers at the University of California, Davis, have discovered a class of natural compounds found within the body that may someday lead to pain relief for millions of diabetics and others suffering ...
Diabetes
Jun 26, 2012 |
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Study identifies adhesion molecules key to cancer's spread through the body
Although tumor metastasis causes about 90 percent of cancer deaths, the exact mechanism that allows cancer cells to spread from one part of the body to another is not well understood. One key question is ...
Cancer
Oct 09, 2012 |
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Newly discovered molecule could deliver drugs to treat diseases
(Medical Xpress)—Kansas State University researchers have discovered a molecule that may be capable of delivering drugs inside the body to treat diseases.
Medical research
Sep 24, 2012 |
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Discovery could reduce chemotherapy's side effects
A team of researchers at Duke University has determined the structure of a key molecule that can carry chemotherapy and anti-viral drugs into cells, which could help to create more effective drugs with fewer effects to healthy ...
Cancer
Mar 11, 2012 |
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A step closer to understanding, averting drug resistance
(Medical Xpress) -- The multidrug transporter EmrE functions as an asymmetric antiparallel dimer (molecule with two subunits). Drug (blue) transport from the inside to the outside of the cell membrane is accomplished ...
Medical research
Jan 31, 2012 |
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Signature of circulating breast tumor cells that spread to the brain found
Some breast tumor circulating cells in the bloodstream are marked by a constellation of biomarkers that identify them as those destined to seed the brain with a deadly spread of cancer, said researchers led by those at Baylor ...
Cancer
Apr 10, 2013 |
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