Structural biologists at St. Jude Children's Research Hospital have determined the detailed structure of an enzyme whose mutated forms are known to cause Parkinson's disease. The achievement opens a research pathway to develop ...
Jun 9, 2021
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Investigators at the Stanford University School of Medicine have shown that removing a matched set of molecules that typically help to regulate the brain's capacity for forming and eliminating connections between nerve cells ...
Mar 21, 2012
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Scientists at The Scripps Research Institute (TSRI) have reported successful preclinical tests of a new vaccine against heroin. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, preventing ...
May 6, 2013
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Duke University researchers have developed a synthetic molecule that selectively dampen the physiological rewards of cocaine in mice. It also may represent a new class of drugs that could be more specific with fewer side ...
May 28, 2020
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Inflammatory bowel disease (IBD), characterized by a chronic inflammation of the digestive tract, is currently treated with steroids and antibody drugs. However, steroids have side effects, such as delayed healing, and antibody ...
Mar 11, 2022
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A Chinese research team joined forces with Russian and U.S. biologists to obtain the crystal structure of the human type 2 cannabinoid receptor. Their findings could lead to drugs against inflammatory, neurodegenerative, ...
Feb 28, 2019
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In recent years, RNA molecules, with the ability to affect or turn off pathogenic genes, have become promising drug candidates in several areas. However, it has been a challenge to develop techniques to deliver the RNA molecules ...
Apr 14, 2020
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A team of scientists led by the Institute of Biomaterials and Bioengineering at Tokyo Medical and Dental University (TMDU) have created novel molecules that prevent human immunodeficiency virus (HIV) particles from attacking ...
Apr 15, 2021
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The future is looking good for drugs designed to combat Alzheimer's disease. EPFL scientists have unveiled how two classes of drug compounds currently in clinical trials work to fight the disease. Their research suggests ...
Aug 2, 2013
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Oral bacteria that escape into the bloodstream are able to cause blood clots and trigger life-threatening endocarditis. Further research could lead to new drugs to tackle infective heart disease, say scientists presenting ...
Mar 26, 2012
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