News tagged with drug resistance
Researchers describe how breast cancer cells acquire drug resistance
A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...
Cancer
May 07, 2013 |
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Genome sequencing provides unprecedented insight into causes of pneumococcal disease
A new study led by researchers from Harvard School of Public Health (HSPH) and the Wellcome Trust Sanger Institute in the UK has, for the first time, used genome sequencing technology to track the changes in a bacterial population ...
Genetics
May 05, 2013 |
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Scientists develop simple blood test to track tumour evolution in cancer patients
By tracking changes in patients' blood, Cambridge scientists have created a new way of looking at how tumours evolve in real-time and develop drug resistance. The research was published in the print edition ...
Cancer
May 03, 2013 |
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Will green tea help you lose weight?
Evidence has shown that green tea extract may be an effective herbal remedy useful for weight control and helping to regulate glucose in type 2 diabetes. In order to ascertain whether green tea truly has this potential, Jae-Hyung ...
Overweight and Obesity
Apr 29, 2013 |
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Gene clues point to Cambodia for resistant malaria
Gene analysis of malaria parasites has pinpointed western Cambodia as the hotspot of strains that are dangerously resistant to artesiminin, the frontline drug against the disease, scientists said on Sunday.
Genetics
Apr 28, 2013 |
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Nanomal smartphone-like malaria detection device to be field tested one year earlier than scheduled
A pioneering mobile device using cutting-edge nanotechnology to rapidly detect malaria infection and drug resistance will be ready for field testing this year, one year ahead of schedule.
Diseases, Conditions, Syndromes
Apr 26, 2013 |
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Researchers make significant step forward in combating antibiotic resistance
The research led by Durham University, which involved colleagues at the University of Birmingham, is a significant development in combating antibiotic resistance; it will pave the way for the creation of the inhibitors to ...
Medical research
Apr 24, 2013 |
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Computer program identifies rare mutations harbored within diverse populations of cancer cells and microorganisms
A tumor is not a uniform mass of identical cells. However, teasing apart genetic heterogeneity within a biopsied tumor can be difficult. Researchers often fail to tell the difference between a rare variant ...
Cancer
Apr 24, 2013 |
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Outpatients, hospital patients face growing, but different problems with antibiotic resistance
A new study concludes that problems with antibiotic resistance faced by outpatients may be as bad as those in hospitalized patients, and that more studies of outpatients are needed – both to protect their health and to ...
Diseases, Conditions, Syndromes
Apr 18, 2013 |
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Despite superbug crisis, progress in antibiotic development 'alarmingly elusive'
Despite the desperate need for new antibiotics to combat increasingly deadly resistant bacteria, the U.S. Food and Drug Administration (FDA) has approved only one new systemic antibiotic since the Infectious Diseases Society ...
Diseases, Conditions, Syndromes
Apr 18, 2013 |
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Antibiotic prescribing rates vary by region
(HealthDay)—The chances that your doctor will give you antibiotics when you're sick may be influenced by geography, new research reveals.
Medications
Apr 10, 2013 |
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Co-Q10 deficiency may relate to concern with statin drugs, higher risk of diabetes
(Medical Xpress)—A laboratory study has shown for the first time that coenzyme Q10 offsets the cellular changes that are linked to a side-effect of some statin drugs - an increased risk of adult-onset diabetes.
Diseases, Conditions, Syndromes
Apr 10, 2013 |
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A hijacking of healthy cellular circuits
Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...
Cancer
Apr 08, 2013 |
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Intermittent treatment with vemurafenib may prevent lethal drug resistance in melanoma
Vemurafenib-resistant tumors in patients with melanoma showed reduced growth after cessation of treatment, and in animal models, drug resistance was prevented by intermittent treatment, according to data presented at the ...
Cancer
Apr 08, 2013 |
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Lift weights to lower blood sugar? White muscle helps keep blood glucose levels under control
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.
Medical research
Apr 07, 2013 |
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Drug resistance
Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.
Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.
Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.
For more information about Drug resistance, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
