News tagged with drug resistance
Genome sequencing provides unprecedented insight into causes of pneumococcal disease
A new study led by researchers from Harvard School of Public Health (HSPH) and the Wellcome Trust Sanger Institute in the UK has, for the first time, used genome sequencing technology to track the changes in a bacterial population ...
Genetics
May 05, 2013 |
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Lift weights to lower blood sugar? White muscle helps keep blood glucose levels under control
Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.
Medical research
Apr 07, 2013 |
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Unchecked antibiotic use in animals may affect global human health
The increasing production and use of antibiotics, about half of which is used in animal production, is mirrored by the growing number of antibiotic resistance genes, or ARGs, effectively reducing antibiotics' ability to fend ...
Medical research
Feb 11, 2013 |
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Study finds mutations linked to relapse of childhood leukemia
After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...
Genetics
Feb 03, 2013 |
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Tuberculosis may lurk in bone marrow stem cells of infected patients, researchers say
Tuberculosis is a devastating disease that kills nearly 2 million people worldwide each year. Although antibiotics exist that can ameliorate the symptoms, the courses of therapy last for months and don't completely eradicate ...
Medical research
Jan 30, 2013 |
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Study: Most-used diabetes drug works in different way than previously thought
A team, led by senior author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Medicine, with the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University ...
Diabetes
Jan 06, 2013 |
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MicroRNAs can convert normal cells into cancer promoters
Unraveling the mechanism that ovarian cancer cells use to change normal cells around them into cells that promote tumor growth has identified several new targets for treatment of this deadly disease.
Cancer
Nov 21, 2012 |
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Low cost pain drug can kill resistant tuberculosis
An off-patent anti-inflammatory drug that costs around two cents for a daily dose in developing countries has been found by researchers at Weill Cornell Medical College to kill both replicating and non-replicating drug resistant ...
Diseases, Conditions, Syndromes
Sep 10, 2012 |
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Low cost pain drug can kill resistant tuberculosis
An off-patent anti-inflammatory drug that costs around two cents for a daily dose in developing countries has been found by researchers at Weill Cornell Medical College to kill both replicating and non-replicating drug resistant ...
Diseases, Conditions, Syndromes
Sep 10, 2012 |
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Mathematical model helps design efficient multi-drug therapies
For years, doctors treating those with HIV have recognized a relationship between how faithfully patients take the drugs they prescribe, and how likely the virus is to develop drug resistance. More recently, research has ...
Medical research
Sep 02, 2012 |
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New drug candidate shows promise against cancer
Drugs containing platinum are among the most powerful and widely used cancer drugs. However, such drugs have toxic side effects, and cancer cells can eventually become resistant to them.
Cancer
Jul 11, 2012 |
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Tumor microenvironment helps skin cancer cells resist drug treatment
One of cancer's most frightening characteristics is its ability to return after treatment. In the case of many forms of cancer, including the skin cancer known as melanoma, tailored drugs can eradicate cancer cells in the ...
Cancer
Jul 04, 2012 |
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Apramycin shows promise against drug-resistant TB and other 'superbugs,' without hearing loss
The world needs new antibiotics to overcome the ever increasing resistance of disease-causing bacteria but it doesn't need the side effect that comes with some of the most powerful ones now available: ...
Medical research
Jun 11, 2012 |
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Novel method combats malaria drug resistance
Researchers from the University of Notre Dame's Eck Institute for Global Health developed a "gene chip" to contribute to the identification of malaria drug resistance, an effort that will allow for real-time response in modified ...
Diseases, Conditions, Syndromes
Apr 05, 2012 |
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Artemisinin-resistant untreatable malaria increasing rapidly along the Thailand-Myanmar border: study
Evidence that the most deadly species of malaria parasite, Plasmodium falciparum, is becoming resistant to the front line treatment for malaria on the border of Thailand and Myanmar (Burma) is reported in The ...
Diseases, Conditions, Syndromes
Apr 05, 2012 |
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Drug resistance
Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used in the context of diseases caused by pathogens.
Pathogens are said to be drug-resistant when drugs meant to neutralize them have reduced effect. When an organism is resistant to more than one drug, it is said to be multidrug resistant.
Drug resistance is an example of evolution in microorganisms. Individuals that are not susceptible to the drug effects are capable of surviving drug treatment, and therefore have greater fitness than susceptible individuals. By the process of natural selection, drug resistant traits are selected for in subsequent offspring, resulting in a population that is drug resistant.
For more information about Drug resistance, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.