New nanoparticles that shut off cancer genes shrink tumors in mice
By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly ...
Cancer
Aug 15, 2012 |
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Genetic risks for type 2 diabetes span multiple ethnicities
A recent large and comprehensive analysis of 50,000 genetic variants across 2,000 genes linked to cardiovascular and metabolic function has identified four genes associated with type 2 diabetes (T2D) and six independent disease-associated ...
Diabetes
Feb 09, 2012 |
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Reinventing drug discovery: Promising drug target for ALS
Using a new stem-cell based drug screening technology with the potential to reinvent and greatly reduce the cost of the way new pharmaceuticals are developed, Harvard Stem Cell Institute (HSCI) researchers ...
Diseases, Conditions, Syndromes
Apr 18, 2013 |
5 / 5 (2) |
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Turning Alzheimer's fuzzy signals into high definition
Scientists at the Virginia Tech Carilion Research Institute have discovered how the predominant class of Alzheimer's pharmaceuticals might sharpen the brain's performance.
Neuroscience
May 07, 2013 |
4.5 / 5 (2) |
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Two Cell Transplantation studies impact dental stem cell research for therapeutic purposes
Two studies appearing in a recent issue of Cell Transplantation (20:11-12), now freely available online, evaluate stem cells derived from dental tissues for characteristics that may make them therapeutically useful and appr ...
Medical research
May 08, 2012 |
4 / 5 (2) |
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Drug development cycle shortened with new silicon-based screening tool
Researchers from A*STAR Institute of Microelectronics (IME) have developed a lateral silicon-based drug screening tool that has demonstrated simultaneous capture of 12 individual cells – 12 times higher ...
Medical research
Jul 20, 2011 |
5 / 5 (1) |
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Sanford-Burnham Medical Research Institute and Pfizer collaborate to speed drug discovery
Sanford-Burnham Medical Research Institute (Sanford-Burnham) is the latest research organization to partner with Pfizer, Inc. as part of Pfizer's commitment to transforming research and development through ...
Medical research
Nov 03, 2011 |
5 / 5 (1) |
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Panel of melanoma mutations opens door to new treatment possibilities
Researchers have developed a new genetic screening tool that will aid in the investigation of possible treatments for patients with melanoma and the unique genetic mutations that may accompany the disease, according to data ...
Cancer
Nov 15, 2011 |
5 / 5 (1) |
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Biomarker family found for chemo resistant breast cancers
Biomarkers which could help to predict resistance to chemotherapy in breast cancer patients have been identified by researchers from the University of Hull, UK.
Cancer
Apr 12, 2012 |
5 / 5 (1) |
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Drug kills cancer cells by restoring faulty tumor suppressor
A new study describes a compound that selectively kills cancer cells by restoring the structure and function of one of the most commonly mutated proteins in human cancer, the "tumor suppressor" p53. The research, published ...
Cancer
May 14, 2012 |
5 / 5 (1) |
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Doctors can now detect hard-to-diagnose prostate cancer
Researchers have successfully developed and tested a new prostate cancer screening method that uses the combined power of a novel drug therapy and changes in PSA levels over time to identify men with a high PSA who are more ...
Cancer
Aug 09, 2012 |
5 / 5 (1) |
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Study finds 'Achilles heel' of key HIV replication protein
Researchers at the University of Pittsburgh School of Medicine may have found an "Achilles heel" in a key HIV protein. In findings published online today in Chemistry and Biology, they showed that targeting this vulnerable spot c ...
HIV & AIDS
Jan 24, 2013 |
5 / 5 (1) |
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Robot hot among surgeons but US taking fresh look (Update)
The biggest thing in operating rooms these days is a million-dollar, multi-armed robot named da Vinci, used in nearly 400,000 surgeries in America last year—triple the number just four years earlier.
Surgery
Apr 09, 2013 |
5 / 5 (1) |
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Researchers work to develop screening method for superbug
A team of researchers from the University of Houston (UH) and St. Luke's Episcopal Hospital (SLEH) are working to develop improved screening methods to detect a potentially lethal, drug-resistant superbug ...
Diseases, Conditions, Syndromes
Sep 09, 2011 |
4 / 5 (1) |
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Novel breast screening technology increases diagnostic accuracy
The addition of three-dimensional breast imaging—a technology called tomosynthesis—to standard digital mammography significantly increases radiologists' diagnostic accuracy while reducing false positive recall rates, ...
Other
Nov 20, 2012 |
4 / 5 (1) |
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