Oncology & Cancer

Evolution of cancer cell lines draws concern

Cell lines form the backbone of cancer research. These individual groups of cells, typically collected from patients' tumor samples and cultured to grow indefinitely in the laboratory, enable everything from basic genetic ...

Diabetes

New link between obesity and diabetes found

A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to ...

Medical research

'Optogenetics' used to control reward-seeking behavior

Using a combination of genetic engineering and laser technology, researchers at the University of North Carolina at Chapel Hill have manipulated brain wiring responsible for reward-seeking behaviors, such as drug addiction. ...

Diseases, Conditions, Syndromes

Harvard undergrad's AI model helps to predict TB resistance

One of the greatest challenges in treating tuberculosis—the top infectious killer worldwide, according to the World Health Organization (WHO)—is the bacterium's ability to shapeshift rapidly and become resistant to multiple ...

Oncology & Cancer

First volume of the Cancer Cell Line Encyclopedia made public

The goal of cancer treatment is to match the right drug to the right target in the right patient. But before such "personalized" drugs can be developed, more knowledge is needed about specific genomic alterations in cancers ...

Medical research

Tale of 2 mice pinpoints major factor for insulin resistance

The road to type 2 diabetes is paved with insulin resistance, a condition often associated with obesity in which the hormone begins to fail at its job helping to convert sugars to energy. Researchers at Joslin Diabetes Center ...

Oncology & Cancer

The path to personalized cancer treatment

In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The study is published in Nature on Thursday 29 ...

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