Scientists find new breast cancer genes, rewrite rulebook
Scientists at the BC Cancer Agency and University of British Columbia have identified new breast cancer genes that could change the way the disease is diagnosed and form the basis of next-generation treatments.
Cancer
Apr 18, 2012 |
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Pancreatic cancer clinical trial results released
The feasibility of selecting treatment based on individual molecular characteristics was demonstrated in a first-of-its kind pancreatic cancer clinical trial reported today by the Translational Genomics Research Institute ...
Cancer
Apr 03, 2012 |
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'Druggable' protein complex identified as a therapeutic target in acute myeloid leukemia
Scientists at Cold Spring Harbor Laboratory have identified a candidate drug target for treating acute myeloid leukemia (AML), a white blood cell cancer that proliferates out of control in the bone marrow. The team, led by ...
Cancer
Apr 02, 2012 |
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Map of substrate-kinase interactions may lead to more effective cancer drugs
(Medical Xpress) -- Later-stage cancers thrive by finding detours around roadblocks that cancer drugs put in their path, but a Purdue University biochemist is creating maps that will help drugmakers close ...
Cancer
Mar 27, 2012 |
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Study reveals new details about a protein that enables cancer cells to start new tumors in distant sites
(Medical Xpress) -- A Loyola University Chicago Stritch School of Medicine study has revealed details of the complex molecular process involving a protein that enables cancer cells to establish tumors in distant parts of ...
Cancer
Mar 14, 2012 |
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Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
In preclinical studies, researchers at SRI International and Astraea Therapeutics have recently evaluated the role of a new drug receptor target that shows promise for the treatment of drug addiction.
Addiction
Mar 14, 2012 |
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Tranylcypromine antidepressant shows promise as cancer treatment
A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more ...
Cancer
Mar 11, 2012 |
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Scientists uncover mechanism for melanoma drug resistance
Cancer is tough to kill and has many ways of evading the drugs used by oncologists to try and eliminate it.
Cancer
Mar 06, 2012 |
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Memory formation triggered by stem cell development
Researchers at the RIKEN-MIT Center for Neural Circuit Genetics have discovered an answer to the long-standing mystery of how brain cells can both remember new memories while also maintaining older ones.
Neuroscience
Feb 23, 2012 |
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Energy network within cells may be new target for cancer therapy
Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the ...
Cancer
Feb 21, 2012 |
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Blocking telomerase kills cancer cells but provokes resistance, progression
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Cancer
Feb 21, 2012 |
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Genetic risks for type 2 diabetes span multiple ethnicities
A recent large and comprehensive analysis of 50,000 genetic variants across 2,000 genes linked to cardiovascular and metabolic function has identified four genes associated with type 2 diabetes (T2D) and six independent disease-associated ...
Diabetes
Feb 09, 2012 |
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Parkinson's disease: Study of live human neurons reveals the disease's genetic origins
Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure.
Parkinson's & Movement disorders
Feb 07, 2012 |
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Research on vitamins could lead to the design of novel drugs to combat malaria
New research by scientists at the University of Southampton could lead to the design of more effective drugs to combat malaria.
Medical research
Jan 27, 2012 |
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Some breast cancer spread may be triggered by a protein, study shows
Cancers rarely are deadly unless they evolve the ability to grow beyond the tissues in which they first arise. Normally, cells -- even early-stage tumor cells -- are tethered to scaffolding that helps to restrain ...
Cancer
Jan 17, 2012 |
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