Genetics
Genetics shed light on causes of intestinal disease
University of Queensland researchers have used genetics to reveal that much of the risk of developing a common and sometimes fatal intestinal disease is inherited.
Jul 5, 2023
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News tagged with drug target
Genetics
Key regulator of COVID viral receptor may be new drug target
Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13 in the open access journal PLOS Biology by ...
Jun 13, 2023
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Oncology & Cancer
CRISPR studies identify many promising therapeutic targets for multiple myeloma
New research from Dana-Farber Cancer Institute has identified 116 genes as key molecular vulnerabilities for multiple myeloma. Most of these genes are potential leads for the discovery of new therapies for this disease. The ...
May 29, 2023
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Addiction
NJ Medicaid reforms tied to increased use of opioid addiction treatment
Reforms to New Jersey's Medicaid program successfully spurred ongoing increases in buprenorphine prescriptions for the treatment of opioid addiction, according to a Rutgers analysis.
May 19, 2023
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Alzheimer's disease & dementia
Scientists use AI to identify likely drug targets in search for Alzheimer's cure
Researchers at the University of Arizona College of Medicine–Tucson, along with collaborators at Harvard University, harnessed the power of artificial intelligence to identify causes of Alzheimer's disease and potential ...
May 16, 2023
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Genetics
CRISPR and single-cell sequencing pinpoint causal genetic variants for traits and diseases
A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does ...
May 4, 2023
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Oncology & Cancer
Lung cancer study finds new target for treatment resistance after EGFR inhibitors
Researchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed on drug-resistant cancer cells in EGFR-mutant non-small cell lung cancer (NSCLC), highlighting a novel therapeutic ...
Feb 13, 2023
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Medical research
Potential new series of drugs targeting cancer-driving protein BCL6
Scientists have revealed details of the discovery of new inhibitors of the BCL6 protein, which is involved in driving several cancer types including the blood cancer B-cell lymphoma.
Feb 9, 2023
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Medications
Investigational drug may combat brain tumors by targeting cancer cells' fat production
Because glioblastoma, a highly aggressive and lethal brain cancer, is resistant to conventional therapies, investigators are searching for characteristics of glioblastoma cells that could point to promising drug targets.
Jan 19, 2023
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Oncology & Cancer
How common genetic alterations cause kidney cancer
An international group of researchers investigated why mutations often associated with renal cancer result specifically in renal cancer, instead of other cancer types.
Aug 9, 2022
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