The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed ...
Jun 4, 2021
0
41
The resilience of cancer cells and their ability to survive in extreme conditions is a large part of what makes cancer so difficult to treat.
Apr 30, 2021
0
73
Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs. This is because antibodies ...
Apr 15, 2021
0
137
Scientists have shown that two existing drug candidates—JAK inhibitors and Mepron—hold potential as treatments for a deadly acute myeloid leukemia (AML) subtype that is more common in children.
Apr 14, 2021
0
51
New clues to a long-pursued drug target in cancer may reside within immune cells, researchers at the University of Michigan Rogel Cancer Center have discovered.
Mar 25, 2021
0
64
For scientists hoping to harness a powerful new technique for demolishing cellular enzymes known as kinases, the choices can be a bit overwhelming. Some 514 different protein kinases toil in human cells, representing 2.5% ...
Dec 3, 2020
0
31
Researchers at the Hong Kong University of Science and Technology (HKUST) have identified new therapeutic targets for Alzheimer's disease (AD) by studying the patients' brain with a newly-developed methodology. This novel ...
Nov 5, 2020
0
107
An international team of researchers has analyzed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells. The research, published in the journal Cell, shows how the virus shifts the cell's ...
Jun 29, 2020
0
820
In the last several years, excitement has surged for a promising class of drugs that work not by inhibiting the action of a molecular target, as most conventional drugs do, but instead by harnessing the cell's recycling system ...
Jun 4, 2020
0
109
Normally, the immune system is able to differentiate between healthy and abnormal cells. Peptides, fragments created by the synthesis and breakdown of proteins inside each cell, are presented on the surface as antigens and ...
Jun 2, 2020
0
79
