A new study has found a molecule hailed as a potential drug candidate for Parkinson's disease is no longer an effective therapeutic option. The WEHI-led research has debunked over 10 years of research that suggested a specific ...
Jan 22, 2024
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Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers ...
Jan 18, 2024
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Whether picking up a small object like a pen or coordinating different body parts, the cerebellum in the brain performs essential functions for controlling our movement. Researchers at the Institute of Science and Technology ...
Jan 11, 2024
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As the cause of chronic inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms. The discovery ...
Jan 10, 2024
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An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain ...
Jan 3, 2024
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Antiseptic mouth rinses containing the active ingredient chlorhexidine (CHX) are widely used in dentistry. For many decades, CHX has set the gold standard for the management of oral diseases. During the treatment, however, ...
Jan 2, 2024
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Scientists at St. Jude Children's Research Hospital have revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases. Leucine-rich repeat kinase 2 (LRRK2) is ...
Dec 21, 2023
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Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids. In most of these diseases, researchers have identified the proteins that aggregate, allowing them to target ...
Dec 6, 2023
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The human immunodeficiency virus (HIV) is a formidable pathogen. It mutates rapidly; in fact, estimates suggest that the genetic diversity of HIV in a single person at one point in time is equal to the diversity of influenza ...
Nov 22, 2023
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A recent study, published in Nature Communications, focuses on the interaction between free fatty acids (FFAs) and GPR84, a G protein-coupled receptor (GPCR).
Nov 22, 2023
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