Medical research

Cellular clock regulating human spine development

More than 20 years ago, the lab of developmental biologist Olivier Pourquié discovered a sort of cellular clock in chicken embryos where each "tick" stimulates the formation of a structure called a somite that ultimately ...

Diseases, Conditions, Syndromes

Sox9 reshapes the biliary tree in Alagille syndrome

Alagille syndrome is a rare pediatric genetic disorder that can affect the liver, heart, kidneys, blood vessels, skeleton and other tissues. One major characteristic of this condition is abnormalities in the ducts that carry ...

Genetics

Cause of rare, fatal disorder in young children pinpointed

Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, ...

Medical research

New mechanism of bone growth discovered

In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden reports that bone growth in mice takes place in accordance with the same principles as when ...

Obstetrics & gynaecology

Folliculin mutations disrupt embryo implantation

New information is unfolding on the genetic controls of an early turning point in pregnancy. As the tiny, dividing cell mass, the blastocyst, travels from the oviduct and lodges in the wall of the uterus, the cells must exit ...

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