Medical research

Making blood on demand: How far have we come?

The reconstitution of the blood system in humans holds great therapeutic potential to treat many disorders, like blood cancers, sickle-cell anemia and others. Successful reconstitution requires the transplantation and engraftment ...

Oncology & Cancer

Scientists discover a new mechanism in childhood kidney cancer

As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched ...

Medical research

Complex organ models grown in the lab

Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.

Medical research

Skin graft: a new molecular target for activating stem cells

Human skin completely renews itself every month thanks to the presence of stem cells in the deepest layer, which generate all the upper layers of this tissue. The deciphering of genes that regulate stemness remains an enigma ...

Cardiology

Mending broken hearts with neural crest cells

Zebrafish—striped fish a few centimeters long—have the ability to regrow up to 20 percent of their hearts after sustaining major damage. Now, Caltech scientists have discovered that embryonic cells from the hindbrain, ...

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