Iron is important for life, and iron deficiency impairs development, but whether the iron level regulates neural differentiation remains elusive. Iron-regulatory proteins (IRPs), including IRP1 and IRP2, are the major regulators ...
Apr 24, 2023
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A preclinical study using stem cells to produce progenitor photoreceptor cells—light-detecting cells found in the eye—and then transplanting these into experimental models of damaged retinas has resulted in significant ...
Apr 14, 2023
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Indiana University School of Medicine researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma.
Mar 10, 2023
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A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
Bone marrow is the spongy tissue inside bone responsible for making red blood cells, white blood cells and platelets. Bone marrow failure syndromes lead to an increased risk of developing dangerous infections, anemia and ...
Mar 2, 2023
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Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...
Mar 1, 2023
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In a first-of-its-kind study, Arizona State University Professor Michael Lynch joins a multi-institute group of researchers to investigate transcription error rates in human cells and the underlying mechanisms affecting them.
Feb 27, 2023
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Tourette syndrome (TS) is a common disorder characterized by uncontrollable motor or vocal tics that manifests in childhood and can interfere with school performance, relationships, and quality of life. Using stem cells from ...
Jan 16, 2023
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83
Building tissues and organs is one of the most complex and important tasks that cells must accomplish during embryogenesis. Individual cells do not make these decisions; rather, building tissue is a collective task that requires ...
Jan 4, 2023
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Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders—especially neurodevelopmental disorders. Novel information ...
Jan 3, 2023
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