Early mammalian development is a highly complex process involving elaborate and highly coordinated biological processes. One such process is zygotic genome activation (ZGA) which occurs following the union of the sperm and ...
Jan 29, 2020
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More than 20 years ago, the lab of developmental biologist Olivier Pourquié discovered a sort of cellular clock in chicken embryos where each "tick" stimulates the formation of a structure called a somite that ultimately ...
Jan 8, 2020
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As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched ...
Dec 18, 2019
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The first signs of Huntington's, an inherited disease that slowly deteriorates bodies and minds, don't typically surface until middle age. But new findings suggest that something in the brain might be amiss long before symptoms ...
Sep 17, 2019
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New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase. Telomerase's only known role in normal tissue was to protect certain cells that divide regularly, ...
Sep 2, 2019
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A newly described form of stress called chromatin architectural defect, or chromatin stress, triggers in cells a response that leads to a longer life. Researchers at Baylor College of Medicine and the Houston Methodist Research ...
Jul 10, 2019
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Pregnant women are often advised to avoid certain drugs because of potential risks to their unborn infant's growing brain cells. Such risks are difficult to pinpoint, though, because there are few ways to track the cellular ...
Jun 17, 2019
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A new approach has enabled researchers to create Expanded Potential Stem Cells (EPSCs) of both pig and human cells. These stem cells have the features of the first cells in the developing embryo, and can develop into any ...
Jun 3, 2019
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Embryonic stem cells (ESC) have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body. The embryonic stem cell state is established and maintained by multiple regulatory ...
Apr 17, 2019
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Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report February 28th in the journal Stem Cell Reports. Single-cell RNA sequencing of human embryonic ...
Feb 28, 2019
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