Gene expression test distinguishes btw breast cancer patients at high and low risk of late recurrence
A test that measures the expression levels of 58 genes in oestrogen receptor-positive breast cancers can effectively differentiate between patients who are at higher and lower risk for having their cancer recur elsewhere ...
Cancer
May 02, 2013 |
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PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer
Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...
Cancer
Apr 01, 2012 |
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25 percent don't complete recommended breast cancer treatment
One-quarter of women who should take hormone-blocking therapies as part of their breast cancer treatment either do not start or do not complete the five-year course, according to a new study led by University of Michigan ...
Cancer
Apr 09, 2013 |
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SABCS: PD 0332991 + letrozole studied in ER+ breast cancer
(HealthDay)—For women with estrogen receptor (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer, the investigational agent PD 0332991 plus letrozole improves progression-free ...
Cancer
Dec 05, 2012 |
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Chemotherapy reduces breast cancer deaths by a third
(Medical Xpress) -- Todays chemotherapy treatments reduce deaths from breast cancer by around a third in a wide range of patients, a giant new analysis of data from over 100 different clinical trials ...
Cancer
Dec 06, 2011 |
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False negative tests in breast cancer may lead to wrong drug choice
A team of Yale Cancer Center researchers has confirmed that between 10-20% of breast cancers classified as Estrogen Receptor (ER) negative are really positive. Understanding when and why breast cancers may be misclassified ...
Cancer
Jun 27, 2011 |
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Imaging agents predict breast cancer response to endocrine therapy
Research published in the July issue of The Journal of Nuclear Medicine shows imaging progesterone receptor (PR) status also may be able to identify responders and nonresponders to endocrine therapy at an early stage. Estrog ...
Cancer
Jul 02, 2012 |
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Obesity linked to worse outcomes in early breast cancer treatment
Obesity is associated with worse outcomes overall in early-stage breast cancer, researchers reported at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 6-10, 2011.
Cancer
Dec 08, 2011 |
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Immediate bisphosphonate use with endocrine therapy increased survival in postmenopausal early breast cancer
The addition of zoledronic acid to adjuvant endocrine therapy increased bone mineral density and reduced the risk for disease recurrence among postmenopausal women with early hormone receptor-positive breast cancer, according ...
Cancer
Dec 07, 2011 |
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