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News tagged with endosomes


Exit discovered in cellular garbage truck: Immersed in the inner workings of a highly selective refuse collection

At the University of Geneva (UNIGE), the team led by Professor Jean Gruenberg has long been interested in the movement of lysosomes, the sub-compartments of cells to where endocytic vesicles deliver their waste content and ...

Medical research created May 09, 2013 | popularity 5 / 5 (1) | comments 0

Misregulated genes may have big autism role

A new study finds that two genes individually associated with rare autism-related disorders are also jointly linked to more general forms of autism. The finding suggests a new genetic pathway to investigate ...

Genetics created Mar 21, 2013 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Targeted gene silencing drugs are more than 500 times more effective with new delivery method

Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically ...

Medical research created Dec 21, 2012 | popularity 5 / 5 (2) | comments 0

Study: Prazosin inhibits endocytic sorting

In a study just published in Proceedings of the National Academy of Sciences, Dr Ulrike Eggert et al. demonstrated that the drug Prazosin inhibits endocytic sorting.

Medical research created Sep 13, 2012 | popularity not rated yet | comments 0

Study reveals insight into how key protein protects against viral infections

Scientists from the University of Utah School of Medicine have discovered that a mouse protein called IFITM3 contributes to the body's defense against some types of viral infections by binding to an enzyme responsible for ...

Immunology created Apr 02, 2012 | popularity not rated yet | comments 0 | with audio podcast

Diametric shift in 2 protein levels spurs Alzheimer's plaque accumulation

A diametric shift in the levels of two proteins involved in folding, moving and cutting other proteins enables accumulation of the destructive brain plaque found in Alzheimer's disease, researchers report.

Medical research created Dec 01, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Poor recycling of BACE1 enzyme could promote Alzheimer's disease

Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology.

Medical research created Nov 21, 2011 | popularity not rated yet | comments 0