A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells. The "Tissue-in-a-CUBE" ...
Feb 28, 2024
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Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly ...
Feb 7, 2024
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Cedars-Sinai Cancer investigators have discovered a protein expressed on multiple myeloma cancer cells that drives disease growth and development. The new study found that blocking part of the protein's unique signaling pathway ...
Feb 7, 2024
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Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial ...
Feb 7, 2024
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Scientists from the German Cancer Research Center (DKFZ) and Heidelberg University have investigated in mice how spreading tumor cells behave at the site of metastasis. Some tumor cells immediately start to form metastases. ...
Feb 2, 2024
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In the human body, the lungs and their vasculature can be likened to a building with an intricate plumbing system. The lungs' blood vessels are the pipes essential for transporting blood and nutrients for oxygen delivery ...
Feb 1, 2024
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A recent collaborative study has developed a microphysiological system to study the effects of COVID-19. The model consists of bronchial organoids and vascular beds and reveals the interactions between the bronchi and vasculature ...
Jan 31, 2024
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It is only a few centimeters in size and can be held between two fingers, but hidden in the micro-channels carved inside it is a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, ...
Jan 22, 2024
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Researchers have revealed new links between Alzheimer's disease and the blood-brain barrier, finding connections between variants of a gene called EphA1 and the disease.
Jan 19, 2024
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A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy ...
Jan 18, 2024
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