News tagged with enzymatic activity

Enzyme catalysis

Enzyme catalysis is the catalysis of chemical reactions by specialized proteins known as enzymes. Catalysis of biochemical reactions in the cell is vital due to the very low reaction rates of the uncatalysed reactions.

The mechanism of enzyme catalysis is similar in principle to other types of chemical catalysis. By providing an alternative reaction route and by stabilizing intermediates the enzyme reduces the energy required to reach the highest energy transition state of the reaction. The reduction of activation energy (ΔG) increases the number of reactant molecules with enough energy to reach the activation energy and form the product.

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Researchers suggest boosting body's natural flu killers

A known difficulty in fighting influenza (flu) is the ability of the flu viruses to mutate and thus evade various medications that were previously found to be effective. Researchers at the Hebrew University of Jerusalem have ...

Diseases, Conditions, Syndromes created May 23, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Loss of essential blood cell gene leads to anemia

Researchers at Brigham and Women's Hospital (BWH) have discovered a new gene that regulates hemoglobin synthesis during red blood cell formation. The findings advance the biomedical community's understanding and treatment ...

Medical research created Nov 07, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers identify gene that leads to myopia (nearsightedness)

A Ben-Gurion University of the Negev research group led by Prof. Ohad Birk has identified a gene whose defect specifically causes myopia or nearsightedness.

Genetics created Sep 01, 2011 | popularity 5 / 5 (2) | comments 2 | with audio podcast

Cold winters freezing out breast cancer treatment

For women diagnosed with a form of breast cancer known as estrogen receptor positive (ER+) breast cancer, tamoxifen is an essential drug used in the treatment and prevention of recurring breast cancer. Currently, tamoxifen ...

Cancer created Apr 18, 2013 | popularity not rated yet | comments 0

The same genetic defect causes Pompe disease in both humans and dogs

Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans. Based ...

Genetics created Feb 15, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Elusive substrate protein identified in the most common form of heritable rickets

(Medical Xpress)—Diagnosed in toddlers, X-linked hypophosphatemia (XLH) is the most common form of heritable rickets, in which soft bones bend and deform, and tooth abscesses develop because infections penetrate soft teeth ...

Medical research created Feb 20, 2013 | popularity not rated yet | comments 0

Study shows additional role for abiraterone in blocking tumor growth in CRPC

As part of an EU-supported IMI-PREDECT consortium (http://www.predect.eu), a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumour growth of ca ...

Cancer created Mar 15, 2013 | popularity not rated yet | comments 0