News tagged with enzyme activity
Study finds plasmin—delivered through a bubble—more effective than tPA in busting clots
A new study from the University of Cincinnati has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots than the standard of care, recombinant tissue plasminogen ...
Cardiology
May 15, 2013 |
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Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging
(Medical Xpress)—Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components ...
Medical research
Apr 12, 2013 |
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Team makes breakthrough in search for neurodegenerative disease treatments
A significant breakthrough has been made by scientists at The University of Manchester towards developing an effective treatment for neurodegenerative diseases such as Huntington's, Alzheimer's and Parkinson's.
Medical research
Apr 10, 2013 |
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The same genetic defect causes Pompe disease in both humans and dogs
Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans. Based ...
Genetics
Feb 15, 2013 |
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Novel technique reveals dynamics of telomere DNA structure
Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural ...
Medical research
Jan 17, 2013 |
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Study demonstrates effects of mutant IDH1 and IDH2 inhibitors in primary tumor models
Agios Pharmaceuticals announced today the publication of two articles in the journal Science by Agios scientists and their collaborators demonstrating the effects of the company's small molecule isocitrate dehydrogenase 1 and ...
Cancer
Apr 04, 2013 |
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South Asians and Europeans react differently to common drugs
(Medical Xpress) -- A University of Sydney PhD student has discovered the different diets and lifestyles of South Asians compared to Europeans could lead to the two groups requiring very different doses of medicines commonly ...
Medications
Oct 14, 2011 |
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Azathioprine may benefit pediatric atopic dermatitis
(HealthDay) -- For pediatric patients with refractory atopic dermatitis (AD), oral azathioprine is associated with clinical improvement, and measurement of thiopurine methyltransferase (TPMT) activity seems ...
Diseases, Conditions, Syndromes
Aug 21, 2012 |
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Ability to metabolize tamoxifen affects breast cancer outcomes, study confirms
For nearly a decade, breast cancer researchers studying the hormone therapy tamoxifen have been divided as to whether genetic differences in a liver enzyme affect the drug's effectiveness and the likelihood breast cancer ...
Cancer
Dec 27, 2012 |
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Analysis does not support genetic test before use of anti-clotting drug
Although the U.S. Food and Drug Administration (FDA) has recommended that a certain type of genetic testing (for the genotype CYP2C19) be considered before prescribing the drug clopidogrel to identify individuals who may ...
Genetics
Dec 27, 2011 |
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Diet rich in vegetables may help stave off acute pancreatitis
A diet rich in vegetables could help stave off the development of the serious condition acute pancreatitis, suggests a large study published online in the journal Gut.
Diseases, Conditions, Syndromes
Jun 27, 2012 |
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New method for diagnosing malaria
Danish researchers have developed a new and sensitive method that makes it possible to diagnose malaria from a single drop of blood or saliva. The method might eventually be used in low-resource areas without ...
Medical research
Nov 27, 2012 |
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Researchers develop more effective way to discover and test potential cancer drugs
Researchers have created a new phenotypic screening platform that better predicts success of drugs developed to prevent blood vessel tumor growth when moving out of the lab and onto actual tumors.
Cancer
Nov 13, 2011 |
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A molecular scissor related to Alzheimer's disease
An international research team led by the Spanish National Research Council (CSIC) and researchers from Kiel University revealed the atomic‐level structure of the human peptidase enzyme meprin β (beta). ...
Alzheimer's disease & dementia
Oct 04, 2012 |
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Studies show that CYP2D6 genotype does not predict tamoxifen benefit
Two studies published March 6 in the Journal of the National Cancer Institute provide insights about the CYP2D6 genotype in postmenopausal breast cancer patients and represent a major step forward in understanding the us ...
Cancer
Mar 06, 2012 |
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