Genetics

Unexpected findings uncover new understanding of gene expression

Northwestern Medicine scientists have discovered that the catalytic activity of the fly enzyme Trr and mammalian MLL3/MLL4—members of the COMPASS family of proteins central to gene expression—is not required for proper ...

Diabetes

New regulator of liver metabolism discovered

Researchers from Charité - Universitätsmedizin Berlin have identified an enzyme that has a major effect on glucose utilization in liver cells. The enzyme, retinol saturase, helps these cells adapt to variations in glucose ...

Oncology & Cancer

'Molecular volume control' may help combat tumours

A 'molecular volume control' may one day be used to manipulate enzyme activity in order control the development and treatment of cancer, according to research at the Universities of Dundee and Bath.

Diseases, Conditions, Syndromes

Study finds key regulator in pulmonary fibrosis

A Yale-led research team has identified an important enzyme that could lead to new therapies for a chronic fatal lung disease that affects hundreds of thousands in the United States each year.

Genetics

Ability to turn off genes in brain crucial for learning, memory

Every time you play a game of basketball, make a cup of coffee or flick on a light switch, you are turning on genes in your brain. These same genes typically are turned off when the activity ceases - but when that doesn't ...

Diseases, Conditions, Syndromes

Even light drinkers should watch for fatty liver disease

People who have reduced enzyme activity to breakdown active aldehyde, i.e., those who become easily inebriated, are more likely to develop fatty liver disease even if they do not drink alcohol. This discovery was made by ...

Genetics

Chromosome 'bumper repair' gene predicts cancer patient outcomes

Like a car's front and back bumpers, your cell's chromosomes are capped by "telomeres" that protect this genetic material against deterioration. Still, after enough replications, a chromosome's telomeres break down and once ...

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