Cancer cells are even smarter than scientists previously believed, according to new CU Boulder research. When these cells are confronted with potent new drugs called CDK2 inhibitors, which are designed to prevent cancer from ...
Jun 15, 2023
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70
A multifaceted intervention to improve prescribing practices increased the likelihood that patients with type 2 diabetes and heart disease would be prescribed three classes of guideline-recommended medications by more than ...
Mar 7, 2023
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24
Targeting cellular post-transcription mechanisms in the CD73 ectoenzyme may promote anti-tumor immunity and slow cancer progression in triple-negative breast cancer, according to a Northwestern Medicine study published in ...
Jan 19, 2023
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43
The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable ...
Sep 22, 2022
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Scientists from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure ...
Apr 5, 2022
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A natural product from the dried root of a pea-family plant, potentially combined with an enzyme inhibitor discovered in the Bruce Hammock laboratory at the University of California, Davis, may provide hope in alleviating ...
Feb 22, 2022
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127
Virtual reality (VR) technology enables scientists to create 3D models of an object and then virtually go "inside" to look around to better understand its structure and function.
Oct 28, 2021
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American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design—blocking a molecular "scissor" that the virus uses for virus production and to disable ...
Oct 16, 2020
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151
Scientists at St. Jude Children's Research Hospital have identified the structure of double-strand DNA break repair by PARP enzymes. The findings show that PARP2 can bridge the gap, bringing two broken DNA ends together.
Sep 16, 2020
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Work published this week in the journal Proceedings of the National Academy of Sciences shows that an enzyme inhibitor developed by Professor Bruce Hammock and colleagues at UC Davis reduced inflammation in the brains of ...
Mar 19, 2019
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