A collaboration between Merck & Co and Codexis, Inc. has resulted in the development of a nine-enzyme, chain-reaction approach for making the HIV drug islatravir. In their paper published in the journal Science, the group ...
Iban Ubarretxena, an Ikerbasque researcher and director of the Biofisika Institute (CSIC-UPV/EHU), participated in a study that identified new inhibitors that could be used to develop drugs to combat Parkinson's. The research ...
Apr 3, 2019
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(MedicalXpress)—A team of researchers with the University of Kentucky has developed a long-term chemical treatment option for cocaine addiction. In their paper published in Proceedings of the National Academy of Sciences, ...
Patients with Parkinson's disease are treated with levodopa, which is converted into dopamine, a neurotransmitter in the brain. In a study published on 18 January in the journal Nature Communications, scientists from the ...
Jan 21, 2019
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The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Jan 13, 2013
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(Medical Xpress)—Apes, including humans, lack an enzyme called uricase that breaks down uric acid. Because we lack uricase, we are predisposed to developing gout. After reconstructing ancient versions of the enzyme found ...
Thanks to the sequencing of the human genome, scientists can now discover potential disorders for which there are no known patients. One such disorder is MPS III-E, originally also called Dierks's disorder after its discoverer. ...
Jan 8, 2018
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A research group in the Faculty of Medicine & Dentistry at the University of Alberta is hoping its latest discovery could one day be used to develop new therapies that target certain types of cancers.
Feb 10, 2012
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A team of researchers from Switzerland, the U.S. and Spain has isolated an enzyme that triggers an autoimmune response from T-cells in patients with MS. In their paper published in the journal Science Translational Medicine, ...
Resistant starch is a non-digestible fiber that ferments in the large intestine, and consumption of it has previously been shown to have a positive effect on metabolism in animal studies.
Sep 5, 2023
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