News tagged with epidermal growth factor receptor
Related topics: patients , breast cancer , cancer , lung cancer , cancer cells
PARP inhibitors may have clinical utility in HER2-positive breast cancers
Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive ...
Cancer
Sep 17, 2012 |
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Cancer-causing gene alone doesn't trigger pancreatic cancer, study finds
More than a cancer-causing gene is needed to trigger pancreatic cancer, a study led by Mayo Clinic has found. A second factor creates a "perfect storm" that allows tumors to form, the researchers say. The study, published ...
Cancer
Sep 10, 2012 |
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Metabolic protein wields phosphate group to activate cancer-promoting genes
A metabolic protein that nourishes cancer cells also activates tumor-promoting genes by loosening part of the packaging that entwines DNA to make up chromosomes, a team led by scientists at The University of Texas MD Anderson ...
Cancer
Aug 16, 2012 |
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Modification of tumor suppressor affects sensitivity to potential GBM treatment
Despite years of research, glioblastoma, the most common and deadly brain cancer in adults, continues to outsmart treatments targeted to inhibit tumor growth.
Cancer
Aug 13, 2012 |
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Decreasing cancer risk associated with inflammatory bowel disease
Inflammatory bowel disease is caused by chronic inflammation , which leads to damage of the intestinal epithelium.
Inflammatory disorders
Jul 09, 2012 |
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New breast cancer genetic alterations discovered
Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...
Cancer
Jun 20, 2012 |
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New breast cancer drug halts tumor growth better than standard therapy
A new cancer treatment that links chemotherapy with an agent that homes in on specific breast cancer cells was significantly better than the current drug regimen at keeping patients' advanced tumors from progressing, according ...
Cancer
Jun 03, 2012 |
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Researchers discover a DNA marker may indicate differences in breast cancer
Researchers and doctors at the North Shore-LIJ Health System and the Feinstein Institute for Medical Research have discovered a potential explanation for why breast cancer is not experienced the same way with African American ...
Cancer
Jun 02, 2012 |
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Team reveals novel way to treat drug-resistant brain tumor cells
New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to current chemotherapies.
Cancer
Jun 01, 2012 |
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The right combination: Overcoming drug resistance in cancer
Overactive epidermal growth factor receptor (EGFR) signaling has been linked to the development of cancer. Several drug therapies have been developed to treat these EGFR-associated cancers; however, many patients have developed ...
Cancer
Jun 01, 2012 |
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Skp2 activates cancer-promoting, glucose-processing Akt
HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.
Cancer
May 25, 2012 |
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Hybrid vaccine demonstrates potential to prevent breast cancer recurrence
A breast cancer vaccine already shown to elicit a powerful immune response in women with varying levels of HER2 expression has the ability to improve recurrence rates and is well tolerated in an adjuvant setting, according ...
Cancer
May 17, 2012 |
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Study combines lapatinib with cetuximab to overcome resistance in EGFR-driven tumors
Targeted therapies have been studied for years, but recent laboratory research is providing robust clues about drugs that might work better in combination, particularly in treating cancers that have become resistant to therapy. ...
Cancer
May 16, 2012 |
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New analysis helps guide use of erlotinib in advanced non-small cell lung cancer
Patients with advanced non-small cell lung cancer should only receive treatment with the drug erlotinib before receiving standard chemotherapy if their tumor is known to harbor EGFR mutations, researchers report at the 3rd ...
Cancer
Apr 18, 2012 |
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Balancing trastuzumab's survival benefits and heart risks for women with breast cancer
Adding trastuzumab (trade name Herceptin) to the treatment offered to women who have HER2-positive breast cancer, significantly increases the chance of life being prolonged, and reduces the chance of tumours reappearing once ...
Cancer
Apr 17, 2012 |
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