News tagged with epigenetic mechanisms


Researchers discover possible trigger for spread of head and neck cancer cells

(Medical Xpress)—Very little has been known about the epigenetic events—developmental and environmental factors affecting genes—that occur prior to the invasive growth of head and neck squamous cell carcinomas and their ...

Cancer created May 08, 2013 | popularity not rated yet | comments 0

Epigenetic changes shed light on biological mechanism of autism

Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in ...

Autism spectrum disorders created Apr 23, 2013 | popularity 3 / 5 (1) | comments 1 | with audio podcast

Soy-based compound may reduce tumor cell proliferation in colorectal cancer

Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer Research 2013 Annual Meeting. ...

Cancer created Apr 11, 2013 | popularity not rated yet | comments 0

The relationship between prenatal stress and obesity is confirmed in rats

The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated ...

Health created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0

KDM1 may represent a new therapeutic target for glioma

Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Researchers link cancer to failures in chromosome protection for the first time

A study published today in the journal Nature Genetics explores a new mechanism that may contribute to the development of several tumours, including Chronic Lymphocytic Leukaemia, a type of cancer that affects more than a ...

Genetics created Mar 19, 2013 | popularity not rated yet | comments 0

Epigenetics mechanism may help explain effects of mom's nutrition on her children's health

Pioneering studies by U. S. Department of Agriculture-funded research molecular geneticist Robert A. Waterland are helping explain how the foods that soon-to-be-moms eat in the days and weeks around the time of conception—or ...

Genetics created Mar 11, 2013 | popularity not rated yet | comments 0

Mechanisms regulating inflammation associated with type 2 diabetes, cancer identified

A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation. Utilizing molecular analyses of gene expression ...

Immunology created Mar 01, 2013 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Life experiences put their stamp on the next generation: New insights from epigenetics

The 18th century natural philosopher Jean-Baptiste Lamarck proposed that the necks of giraffes lengthened as a consequence of the cumulative effort, across generations, to reach leaves just out of their grasp. This view of ...

Psychology & Psychiatry created Feb 14, 2013 | popularity 5 / 5 (1) | comments 0

Colon cancer exhibits a corresponding epigenetic pattern in mice and humans

Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between ...

Genetics created Feb 07, 2013 | popularity not rated yet | comments 0 | with audio podcast

Replicating risk genes in bipolar disorder

One of the biggest challenges in psychiatric genetics has been to replicate findings across large studies.

Psychology & Psychiatry created Oct 15, 2012 | popularity 5 / 5 (3) | comments 0

The molecular mechanisms behind the benefits of exercise

Leading a sedentary lifestyle increases risk of developing type 2 diabetes. European scientists focused on delineating the mechanisms responsible for the beneficial effects of exercise on our metabolism.

Other created Sep 20, 2012 | popularity not rated yet | comments 0

Cell contents may be key to controlling toxicity of Huntington's disease protein

New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.

Genetics created Jun 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Epigenetics and epidemiology -- hip, hype and science

Epigenetics is the new hip science. Time Magazine's front cover and article, 'Why your DNA isn't your Destiny' from January 2010 explains why. Its more explicit subtitle provided the hook - 'The new science of epigenetics ...

Genetics created Mar 15, 2012 | popularity not rated yet | comments 0

Gene regulator in brain's executive hub tracked across lifespan

For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain's executive hub. Among key findings ...

Autism spectrum disorders created Feb 02, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast