Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study ...
Mar 6, 2024
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In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have ...
Mar 6, 2024
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When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...
Feb 28, 2024
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The candidate gene FKBP5 is involved in the development of stress-related psychiatric disorders. A few years ago, researchers at the MPI discovered that it is increasingly activated in the brains of patients and can permanently ...
Feb 27, 2024
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Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes. They also demonstrated ...
Feb 21, 2024
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A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered. That means the patients' behavior or environment has caused changes that affect the way their genes ...
Feb 10, 2024
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The epigenetic 'signature' of a rare, hard-to-diagnose breast tumor has been found by scientists at the Garvan Institute of Medical Research. The discovery could lead to improved treatment guidelines and better outcomes for ...
Feb 2, 2024
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Experiments with rats conducted by researchers at São Paulo State University (UNESP) in Brazil increase our understanding of why descendants of women who were malnourished during pregnancy tend to face a higher risk of prostate ...
Jan 24, 2024
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A recent study has reported that changes in mice sperm microRNAs brought about by aging may affect the growth and development of offspring. The finding adds to the growing literature on the effects of paternal aging on offspring.
Jan 12, 2024
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Like a criminal entering a witness protection program, cancer cells can shed their past and take on a new identity. Detecting such an identity switch is particularly challenging when metastatic castration-resistant prostate ...
Jan 10, 2024
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