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News tagged with epigenomes


Novel microscale epigenomics technology: Possible to study the epigenome of rare cell populations and biopsy samples

Scientists at A*STAR's Genome Institute of Singapore (GIS) have successfully developed a method to map the epigenome using 100 times fewer cells than was previously possible. The discovery, published in the journal Developmental Ce ...

Genetics created Feb 11, 2013 | popularity 5 / 5 (1) | comments 0

Study finds hormones can change the breast's genetic material

Melbourne scientists have discovered how female steroid hormones can make dramatic changes to the genetic material in breast cells, changes that could potentially lead to breast cancer.

Medical research created Jan 31, 2013 | popularity not rated yet | comments 0 | with audio podcast

SNPs associated with breast cancer risk alter binding affinity for pioneer factor FOXA1

Dartmouth scientists showed that more than half of all the SNPs associated with breast cancer risk are located in distant regions and bound by FOXA1, a protein required for estrogen receptor-α (ER) function according to ...

Cancer created Jan 23, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers unravel the first epigenomes of chronic lymphocytic leukemia

Researchers of the University of Oviedo have contributed to decipher the first epigenomes of chronic lymphocytic leukemia. Professor of Biochemistry and Molecular Biology Carlos López-Otín and two members ...

Cancer created Oct 22, 2012 | popularity not rated yet | comments 0

Differences between human twins at birth highlight importance of intrauterine environment

Your genes determine much about you, but environment can have a strong influence on your genes even before birth, with consequences that can last a lifetime. In a study published online in Genome Research, researchers have f ...

Genetics created Jul 15, 2012 | popularity 4.5 / 5 (4) | comments 9 | with audio podcast

Study: The epigenome of newborns and centenarians is different

What happens in our cells after one hundred years? What is the difference at the molecular level between a newborn and a centenary? Is it a gradual or a sudden change? Is it possible to reverse the aging process? What are ...

Genetics created Jun 11, 2012 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Researchers complete the first epigenome in Europe

A study led by Manel Esteller, director of the Epigenetics and Cancer Biology Program at the Bellvitge Biomedical Research Institute (IDIBELL), professor of genetics at the University of Barcelona and ICREA researcher, has ...

Genetics created May 30, 2012 | popularity not rated yet | comments 0

Changes in genetic function in the brain linked to Alzheimer's

Changes in the epigenome, a structure that controls the function of genes, were found in the brains of Alzheimer's patients.

Alzheimer's disease & dementia created Apr 20, 2012 | popularity not rated yet | comments 0

Cancer cells' universal 'dark matter' exposed

Using the latest gene sequencing tools to examine so-called epigenetic influences on the DNA makeup of colon cancer, a Johns Hopkins team says its results suggest cancer treatment might eventually be more tolerable and successful ...

Cancer created Jun 26, 2011 | popularity 4.4 / 5 (8) | comments 0 | with audio podcast

Researchers characterize epigenetic fingerprint of 1,628 people

Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show ...

Genetics created Jun 02, 2011 | popularity 5 / 5 (3) | comments 0