News tagged with erythropoietin
Erythropoietin
Erythropoietin, or its alternatives erythropoetin or erithropoyetin ( /ɨˌrɪθrɵˈpɔɪ.ɨtɨn/, /ɨˌrɪθrɵˈpɔɪtən/, or /ɨˌriːθrɵ-/) or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow.
Also called hematopoietin or hemopoietin, it is produced by interstitial fibroblasts in the kidney in close association with peritubular capillary and tubular epithelial cells. It is also produced in perisinusoidal Ito cells in the liver. While liver production predominates in the fetal and perinatal period, renal production is predominant during adulthood. Erythropoietin is the hormone that regulates red blood cell production. It also has other known biological functions. For example, erythropoietin plays an important role in the brain's response to neuronal injury. EPO is also involved in the wound healing process.
When exogenous EPO is used as a performance-enhancing drug, it is classified as an erythropoiesis-stimulating agent (ESA). Exogenous EPO can often be detected in blood, due to slight difference from the endogenous protein, for example in features of posttranslational modification.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
EPO doping in elite cycling: No evidence of benefit, but high risk of harm
The drug erythropoietin, often called EPO, is banned from sports because it is believed to enhance an athlete's performance and give people who use it an unfair advantage over unenhanced competitors. However a new systemic ...
Health
Dec 05, 2012 |
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Duke research team identifies a potent growth factor for blood stem cells
Duke Medicine researchers studying the interaction of blood stem cells and the niche where they reside have identified a protein that may be a long-sought growth factor for blood stem cells.
Medical research
Oct 23, 2012 |
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As Armstrong case unfolds, experts describe doping's harms
(HealthDay)—In the wake of new allegations around Lance Armstrong's involvement in blood doping, experts are reminding the public of the devastating impact these substances can have on an athlete's health. ...
Health
Oct 11, 2012 |
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Don't feel like exercise? Scientists find compound that may help you work out harder
As science rushes to develop safe weight loss drugs, a new research report approaches this problem from an entirely new angle: What if there were a pill that would make you want to exercise harder? It may sound strange, but ...
Medical research
Jun 12, 2012 |
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Biker's warning! Erythropoietin hits blood vessels to raise blood pressure in the brain
Erythropoietin or EPO might be considered a "performance enhancing" substance for athletes, but new research published online in The FASEB Journal shows that these enhancements come at a high cost--increased risk of vascul ...
Medical research
Dec 10, 2011 |
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Study examines outcomes of erythropoietin use for heart attack patients undergoing PCI
Intravenous administration of epoetin alfa, a product that stimulates red blood cell production, to patients with heart attack who were undergoing percutaneous coronary intervention (PCI; procedures such as balloon angioplasty ...
Medical research
May 10, 2011 |
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