News tagged with estrogen receptor

Related topics: women · breast cancer · cancer cells · estrogen

Team develops prognostic test for E2F4 in breast cancer

By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center (NCCC), led by Chao Cheng, PhD, have identified a gene signature ...

Jan 07, 2015
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Estrogen receptor

Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.

The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.

This text uses material from Wikipedia, licensed under CC BY-SA

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