News tagged with estrogen receptor
New breast cancer genetic alterations discovered
Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...
Cancer
Jun 20, 2012 |
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Scientists decode DNA to find breast tumor signatures that predict treatment response
Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering ...
Genetics
Jun 10, 2012 |
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Three new genetic links to breast cancer identified
(Medical Xpress) -- An international team of researchers has identified three new genetic loci associated with an increased susceptibility to breast cancer. As described in their paper published in Nature Ge ...
Genetics
Jan 23, 2012 |
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Study reveals new mechanism for estrogen suppression of liver lipid synthesis
By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.
Medical research
16 hours ago |
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Estrogen may improve pathway-selective insulin resistance
(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin ...
Diabetes
Feb 14, 2013 |
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BPA substitute could spell trouble: Experiments show bisphenol S also disrupts hormone activity
A few years ago, manufacturers of water bottles, food containers, and baby products had a big problem. A key ingredient of the plastics they used to make their merchandise, an organic compound called bisphenol A, had been ...
Health
Jan 22, 2013 |
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New finding gives clues for overcoming tamoxifen-resistant breast cancer
(Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients ...
Cancer
Nov 02, 2012 |
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BPA's real threat may be after it has metabolized
Bisphenol A or BPA is a synthetic chemical widely used in the making of plastic products ranging from bottles and food can linings to toys and water supply lines. When these plastics degrade, BPA is released ...
Health
Oct 04, 2012 |
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Breast cancer recurrence defined by hormone receptor status
Human epidermal growth factor (HER2) positive breast cancers are often treated with the same therapy regardless of hormone receptor status. New research published in BioMed Central's open access journal Breast Cancer Research shows ...
Cancer
Oct 01, 2012 |
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Researchers identify gene partly responsible for maternal care in mice
(Medical Xpress)—The medial preoptic area of the brain has been found over the years to be very closely involved with certain behaviors in mice, such as sexual proclivity, locomotion, aggression and the ...
Genetics
Sep 18, 2012 |
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Single protein promotes resistance to widely used anti-estrogen drugs
Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.
Cancer
Jul 02, 2012 |
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HIV drug may slow down metastatic breast cancer
The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue ...
Cancer
Jun 06, 2012 |
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Study links breast cancer resistance with timing of soy consumption
Studies exploring the relationship between soy consumption and breast cancer have been mixed, but new research introduces a new thought: Could women with breast cancer who began eating soy as an adult develop a tumor more ...
Cancer
Apr 02, 2012 |
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Even a little drinking may raise breast cancer risk: study
(HealthDay) -- Just one alcoholic drink a day can boost a woman's risk of breast cancer by about 5 percent, according to a new review of existing research.
Cancer
Mar 29, 2012 |
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Study shows estrogen works in the brain to keep weight in check
A recent UT Southwestern Medical Center study found that estrogen regulates energy expenditure, appetite and body weight, while insufficient estrogen receptors in specific parts of the brain may lead to obesity.
Medical research
Oct 20, 2011 |
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Estrogen receptor
Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
For more information about Estrogen receptor, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.