News tagged with estrogen receptor

New breast cancer genetic alterations discovered

Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...

Cancer created Jun 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists decode DNA to find breast tumor signatures that predict treatment response

Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering ...

Genetics created Jun 10, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Three new genetic links to breast cancer identified

(Medical Xpress) -- An international team of researchers has identified three new genetic loci associated with an increased susceptibility to breast cancer. As described in their paper published in Nature Ge ...

Genetics created Jan 23, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast report

Study reveals new mechanism for estrogen suppression of liver lipid synthesis

By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.

Medical research created 16 hours ago | popularity not rated yet | comments 0 | with audio podcast

Estrogen may improve pathway-selective insulin resistance

(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin ...

Diabetes created Feb 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

BPA substitute could spell trouble: Experiments show bisphenol S also disrupts hormone activity

A few years ago, manufacturers of water bottles, food containers, and baby products had a big problem. A key ingredient of the plastics they used to make their merchandise, an organic compound called bisphenol A, had been ...

Health created Jan 22, 2013 | popularity 5 / 5 (9) | comments 1 | with audio podcast

New finding gives clues for overcoming tamoxifen-resistant breast cancer

(Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients ...

Cancer created Nov 02, 2012 | popularity not rated yet | comments 0 | with audio podcast

BPA's real threat may be after it has metabolized

Bisphenol A or BPA is a synthetic chemical widely used in the making of plastic products ranging from bottles and food can linings to toys and water supply lines. When these plastics degrade, BPA is released ...

Health created Oct 04, 2012 | popularity 5 / 5 (9) | comments 0 | with audio podcast

Breast cancer recurrence defined by hormone receptor status

Human epidermal growth factor (HER2) positive breast cancers are often treated with the same therapy regardless of hormone receptor status. New research published in BioMed Central's open access journal Breast Cancer Research shows ...

Cancer created Oct 01, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers identify gene partly responsible for maternal care in mice

(Medical Xpress)—The medial preoptic area of the brain has been found over the years to be very closely involved with certain behaviors in mice, such as sexual proclivity, locomotion, aggression and the ...

Genetics created Sep 18, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast report

Single protein promotes resistance to widely used anti-estrogen drugs

Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.

Cancer created Jul 02, 2012 | popularity not rated yet | comments 0 | with audio podcast

HIV drug may slow down metastatic breast cancer

The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue ...

Cancer created Jun 06, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study links breast cancer resistance with timing of soy consumption

Studies exploring the relationship between soy consumption and breast cancer have been mixed, but new research introduces a new thought: Could women with breast cancer who began eating soy as an adult develop a tumor more ...

Cancer created Apr 02, 2012 | popularity not rated yet | comments 0 | with audio podcast

Even a little drinking may raise breast cancer risk: study

(HealthDay) -- Just one alcoholic drink a day can boost a woman's risk of breast cancer by about 5 percent, according to a new review of existing research.

Cancer created Mar 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study shows estrogen works in the brain to keep weight in check

A recent UT Southwestern Medical Center study found that estrogen regulates energy expenditure, appetite and body weight, while insufficient estrogen receptors in specific parts of the brain may lead to obesity.

Medical research created Oct 20, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Estrogen receptor

Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.

The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.

For more information about Estrogen receptor, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: women , breast cancer , cancer cells , estrogen