News tagged with estrogen receptor
Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...
Cancer Jun 20, 2012 | not rated yet | 0 |
Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering ...
Genetics Jun 10, 2012 | 4.8 / 5 (4) | 0 |
(Medical Xpress) -- An international team of researchers has identified three new genetic loci associated with an increased susceptibility to breast cancer. As described in their paper published in Nature Ge ...
Genetics Jan 23, 2012 | 5 / 5 (1) | 0 |
By discovering the new mechanism by which estrogen suppresses lipid synthesis in the liver, UC Irvine endocrinologists have revealed a potential new approach toward treating certain liver diseases.
Medical research 16 hours ago | not rated yet | 0 |
(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin ...
Diabetes Feb 14, 2013 | not rated yet | 0 |
A few years ago, manufacturers of water bottles, food containers, and baby products had a big problem. A key ingredient of the plastics they used to make their merchandise, an organic compound called bisphenol A, had been ...
Health Jan 22, 2013 | 5 / 5 (9) | 1 |
(Medical Xpress)—A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients ...
Cancer Nov 02, 2012 | not rated yet | 0 |
Bisphenol A or BPA is a synthetic chemical widely used in the making of plastic products ranging from bottles and food can linings to toys and water supply lines. When these plastics degrade, BPA is released ...
Health Oct 04, 2012 | 5 / 5 (9) | 0 |
Human epidermal growth factor (HER2) positive breast cancers are often treated with the same therapy regardless of hormone receptor status. New research published in BioMed Central's open access journal Breast Cancer Research shows ...
Cancer Oct 01, 2012 | not rated yet | 0 |
(Medical Xpress)—The medial preoptic area of the brain has been found over the years to be very closely involved with certain behaviors in mice, such as sexual proclivity, locomotion, aggression and the ...
Genetics Sep 18, 2012 | 5 / 5 (1) | 0 |
Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.
Cancer Jul 02, 2012 | not rated yet | 0 |
The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue ...
Cancer Jun 06, 2012 | not rated yet | 0 |
Studies exploring the relationship between soy consumption and breast cancer have been mixed, but new research introduces a new thought: Could women with breast cancer who began eating soy as an adult develop a tumor more ...
Cancer Apr 02, 2012 | not rated yet | 0 |
(HealthDay) -- Just one alcoholic drink a day can boost a woman's risk of breast cancer by about 5 percent, according to a new review of existing research.
Cancer Mar 29, 2012 | not rated yet | 0 |
A recent UT Southwestern Medical Center study found that estrogen regulates energy expenditure, appetite and body weight, while insufficient estrogen receptors in specific parts of the brain may lead to obesity.
Medical research Oct 20, 2011 | 5 / 5 (1) | 0 |
Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
For more information about Estrogen receptor, read the full article at
This text uses material from Wikipedia and is available under the GNU Free Documentation License.