News tagged with estrogen receptor

Related topics: women , breast cancer , cancer cells , estrogen

BPA affects sex-based behavior in mice

(Medical Xpress)—Bisphenol A (BPA) is a common chemical found in household plastics. Previous studies on rodents show that BPA exposure is associated with problems with brain and behavioral development. ...

May 28, 2013
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New breast cancer genetic alterations discovered

Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...

Jun 20, 2012
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Estrogen receptor

Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.

The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.

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