Uterine cancers that developed in patients treated with tamoxifen (Soltamox) had fewer PI3K pathway mutations and may have instead been driven by tamoxifen-induced PI3K pathway activation, according to results presented at ...
Dec 9, 2021
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A non-invasive, patient-friendly imaging technique can help physicians make treatment decisions for breast cancer patients when diagnostic dilemmas arise. The 18F-FES PET scan—approved by the U.S. Food and Drug Administration ...
Sep 29, 2021
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Early results from a UCLA-led clinical trial found treating women with estrogen receptor (ER)-positive and human epidermal growth factor receptor-2 (HER2)-negative early breast cancers with a novel type of anti-hormonal ...
Sep 20, 2021
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Scientists working to understand the cellular processes linking high cholesterol to breast cancer recurrence and metastasis report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting ...
Jun 9, 2021
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The lifetime risk of breast cancer is similar among Black and white women in the U.S., but Black women are disproportionately affected by aggressive breast cancer subtypes such as estrogen receptor (ER) negative tumors, which ...
May 24, 2021
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In a study carried out in mice at the University of Chicago, researchers found that lasofoxifene outperformed fulvestrant, the current gold-standard drug, in reducing or preventing primary tumor growth. It also was more effective ...
May 13, 2021
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(HealthDay)—More patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2-negative breast cancer have been treated with neoadjuvant endocrine therapy (NET) due to COVID-19, according to a ...
May 3, 2021
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A small proportion of women who receive anti-estrogen treatment after breast cancer surgery have worse outcomes. This is associated with mutations in the estrogen receptor gene, according to a study from Lund University now ...
Apr 22, 2021
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Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast. It covers 10 to 15% of all breast cancer cases, has a high risk of late recurrence, unique metastatic ...
Feb 22, 2021
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Oral contraceptives are implicated in slightly increasing breast cancer risk. This birth control method contains forms of estrogen, a hormone that binds ERalpha (estrogen receptor alpha), to alter the reproductive cycle. ...
Aug 10, 2020
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