Dietary medium chain triglycerides prevent nonalcoholic fatty liver disease
Scientists at the Arkansas Children's Nutrition Center, a U.S. Department of Agriculture Agricultural Research Service Human Nutrition Research Center at the University of Arkansas for Medical Sciences, led by Dr. Martin ...
Diseases, Conditions, Syndromes
Apr 24, 2013 |
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Repairing articular cartilage defects with an injectable gel engineered with gene modified BMSCs
Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hydrogel engineered with ...
Arthritis & Rheumatism
Apr 23, 2013 |
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Epoxide hydrolase inhibition and Thiazolidinediones: A therapy for cardiometabolic syndrome
Scientists at the Medical College of Wisconsin and the University of California at Davis, led by Dr. John Imig and Dr. Bruce Hammock have determined the synergistic actions of inhibiting soluble epoxide hydrolase (sEH) with ...
Diseases, Conditions, Syndromes
Apr 23, 2013 |
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Improving the development of new cancer models using an advanced biomedical imaging method
Scientists at the University of Arizona Cancer Center and the Moffitt Cancer Center, led by Dr. Robert Gillies, have demonstrated that an advanced magnetic resonance imaging (MRI) method can non-invasively evaluate the cellular ...
Cancer
Dec 17, 2012 |
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Oxidative stress and altered gene expression occurs in a metabolic liver disease model
A team of researchers under the direction of Dr. Jeffrey Teckman in the Department of Pediatrics at St. Louis University, have demonstrated that oxidative stress occurs in a genetic model of alpha-1-antitrypsin deficiency. ...
Medical research
Oct 30, 2012 |
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'Kick-starting' male fertility
Adding a missing protein to infertile human sperm can 'kick-start' its ability to fertilise an egg and dramatically increase the chances of a successful pregnancy, a team of Cardiff University scientists have uncovered.
Medical research
Sep 21, 2012 |
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Lack of sleep affects bone health and bone marrow activity
Scientists at the Medical College of Wisconsin, in a team led by Carol Everson, Ph.D., professor of neurology, cell biology, neurobiology and anatomy, have discovered abnormalities in bone and bone marrow in rats undergoing ...
Medical research
Sep 18, 2012 |
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pH-sensitive liposomal cisplatin improves peritoneal carcinomatosis treatment without side-effects
Scientists at the Oswaldo Cruz Foundation and Federal University of Minas Gerais, led by Dr. Andréa Teixeira-Carvalho and Dr. Mônica Cristina de Oliveira, have developed and characterized a circulating and pH-sensitive ...
Medical research
Aug 27, 2012 |
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Treating drug resistant cancer through targeted inhibition of sphingosine kinase
Scientists at Tulane University School of Medicine, led by Dr. James Antoon and Dr. Barbara Beckman, have characterized two drugs targeting sphingosine kinase (SK), an enzyme involved in cancer growth and metastasis. New ...
Cancer
Aug 09, 2012 |
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An economical, effective and biocompatible gene therapy strategy promotes cardiac repair
Dr Changfa Guo, Professor Chunsheng Wang and their co-investigators from Zhongshan hospital Fudan University, Shanghai, China have established a novel hyperbranched poly(amidoamine) (hPAMAM) nanoparticle based hypoxia regulated ...
Medical research
Jul 06, 2012 |
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Identification of differential proteins in maternal serum with Down syndrome
Prenatal screening for Down syndrome (DS) is still in need of improvement. Perinatal medicine experts have worked hard to find new biomarkers for screening of DS. Dr. Shi he Shao and his co-investigators, from Jiangsu University ...
Medical research
Jun 07, 2012 |
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Study reveals how the world's first drug for amyloid disease works
Scientists from The Scripps Research Institute and Pfizer Inc. have published a new study showing how a new drug called tafamidis (Vyndaqel) works. Tafamidis, approved for use in Europe and currently under ...
Medical research
May 29, 2012 |
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A breakthrough in understanding the biology and treatment of ovarian cancer
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the presence and integrity of the opioid growth factor receptor (OGFr), which mediates the inhibitory action ...
Cancer
Feb 21, 2012 |
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ISG15: A novel therapeutic target to slow breast cancer cell motility
Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and ...
Cancer
Jan 11, 2012 |
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New research finds trigger for breast cancer spread
Research led by Shyamal Desai, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has discovered a key change in the body's defense system that increases the potential ...
Cancer
Jan 03, 2012 |
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