News tagged with experimental therapeutics
Pathological gambling caused by excessive optimism
Compulsive gamblers suffer from an optimism bias that modifies their subjective representation of probability and affects their decisions in situations involving high-risk monetary wagers. This is the conclusion drawn by ...
Psychology & Psychiatry
Apr 30, 2013 |
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New agent might control breast-cancer growth and spread
A new study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) suggests that an unusual ...
Cancer
Apr 22, 2013 |
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Blood tests can provide fuller picture of mutations in cancer than traditional biopsies do
A new blood test revealed more of the gene mutations that sustain certain digestive-tract tumors than did a DNA analysis of a traditional tumor biopsy, Dana-Farber Cancer Institute investigators will report at a special symposium ...
Cancer
Apr 07, 2013 |
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Study offers new targets for stroke treatments
New research from the University of Georgia identifies the mechanisms responsible for regenerating blood vessels in the brain.
Medical research
Dec 20, 2012 |
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Alzheimer's disease in mice alleviated promising therapeutic approach for humans
Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité - Universitätsmedizin Berlin and the University ...
Alzheimer's disease & dementia
Nov 25, 2012 |
5 / 5 (10) |
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Mice with 'humanized' livers improve early drug testing
Stanford University School of Medicine scientists have used bioengineered mice with livers composed largely of human cells to characterize a drug about to enter early-stage clinical development for combating hepatitis C.
Medical research
Oct 31, 2012 |
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Oxidative stress and altered gene expression occurs in a metabolic liver disease model
A team of researchers under the direction of Dr. Jeffrey Teckman in the Department of Pediatrics at St. Louis University, have demonstrated that oxidative stress occurs in a genetic model of alpha-1-antitrypsin deficiency. ...
Medical research
Oct 30, 2012 |
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Prospective Alzheimer's drug builds new brain cell connections
Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.
Alzheimer's disease & dementia
Oct 11, 2012 |
5 / 5 (8) |
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Genetically-engineered preclinical models predict pharmacodynamic response
New cancer drugs must be thoroughly tested in preclinical models, often in mice, before they can be offered to cancer patients for the first time in phase I clinical trials. Key components of this process include pharmacokinetic ...
Cancer
Sep 19, 2012 |
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pH-sensitive liposomal cisplatin improves peritoneal carcinomatosis treatment without side-effects
Scientists at the Oswaldo Cruz Foundation and Federal University of Minas Gerais, led by Dr. Andréa Teixeira-Carvalho and Dr. Mônica Cristina de Oliveira, have developed and characterized a circulating and pH-sensitive ...
Medical research
Aug 27, 2012 |
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Experimental drug may extend therapeutic window for stroke
A team led by a physician-scientist at the University of Southern California (USC) has created an experimental drug that reduces brain damage and improves motor skills among stroke-afflicted rodents when given with federally ...
Cardiology
Jul 17, 2012 |
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Studies show that pancreatic cancer can run but not always hide from the immune system
A pair of recent studies describes how pancreatic cancer cells produce a protein that attracts the body's immune cells and tricks them into helping cancer cells grow. The research, published by Cell Press in the June 12th ...
Cancer
Jun 11, 2012 |
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Clinical trial design supports original accelerated approval of sunitinib for GIST
Patients benefitted from an important design element in the pivotal phase III clinical trial that led to Food and Drug Administration and worldwide regulatory approval of sunitinib for the treatment of gastrointestinal stromal ...
Cancer
Jun 01, 2012 |
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H5N1 bird flu diagnostic kit detects all known strains of virus with a single test
A close collaboration between scientists from the Experimental Therapeutics Centre (ETC) under the Agency for Science and Technology Research (A*STAR) and clinicians from Tan Tock Seng Hospital (TTSH) has enabled the successful ...
Diseases, Conditions, Syndromes
May 29, 2012 |
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Dabrafenib shrinks melanoma brain metastases in phase I clinical trial
An experimental drug targeting a common mutation in melanoma successfully shrank tumors that spread to the brain in nine out of 10 patients in part of an international phase I clinical trial report in the May 18 issue of ...
Cancer
May 17, 2012 |
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