Discovery offers unprecedented look at regulation of gene expression
(Medical Xpress)—A groundbreaking technique developed at the University of Virginia School of Medicine is allowing scientists to examine histone modifications of genetic loci – a process that regulates gene expression ...
Medical research
Jan 25, 2013 |
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New mutations driving malignant melanoma discovered
Two new mutations that collectively occur in 71 percent of malignant melanoma tumors have been discovered in what scientists call the "dark matter" of the cancer genome, where cancer-related mutations haven't ...
Cancer
Jan 24, 2013 |
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A scanner for hereditary defects
Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. ...
Genetics
Jan 24, 2013 |
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Blood test might help guide pancreatic cancer treatment
(HealthDay)—A simple blood test might help predict a pancreatic cancer patient's chances of benefiting from chemotherapy, a small study suggests.
Cancer
Jan 23, 2013 |
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Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases
In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...
Cancer
Jan 23, 2013 |
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New test predicted presence of harmful BRCA mutations
A new multiple gene expression profile test was able to predict the presence of harmful BRCA1 or BRCA2 mutations in otherwise healthy women carrying the mutations, according to data published in Cancer Prevention Research, a jour ...
Cancer
Jan 22, 2013 |
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Expression, genomic patterns predict sarcoma progression
(HealthDay)—The Complexity Index in Sarcoma (CINSARC) and Genomic Index prognostic signatures are valid independent methods of assessing synovial sarcoma (SS) prognosis, according to a study published online ...
Cancer
Jan 18, 2013 |
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Hepatitis B virus promotes oncogenesis through microRNA modulation
Viruses prompt oncogenic transformation by genetically altering infected cells. Several recent studies have demonstrated that viruses alter the expression of microRNAs, non-coding RNA molecules that can block the expression ...
Diseases, Conditions, Syndromes
Jan 16, 2013 |
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Possible role for Huntington's gene discovered
About 20 years ago, scientists discovered the gene that causes Huntington's disease, a fatal neurodegenerative disorder that affects about 30,000 Americans. The mutant form of the gene has many extra DNA ...
Genetics
Jan 16, 2013 |
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Don't read my lips! Body language trumps the face for conveying intense emotions
Be it triumph or crushing defeat, exhilaration or agony, body language more accurately conveys intense emotions, according to recent research that challenges the predominance of facial expressions as an indicator of how a ...
Psychology & Psychiatry
Jan 15, 2013 |
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Scientists reveal aggressive breast cancer's metastatic path
Scientists at Weill Cornell Medical College have discovered the molecular switch that allows aggressive triple negative breast cancer cells to grow the amoeba-like protrusions they need to crawl away from a primary tumor ...
Cancer
Jan 14, 2013 |
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Team finds gene that promotes drug resistance in cancer
Scientists from the University of Iowa and Brigham Young University (BYU) have identified a gene that may be a target for overcoming drug resistance in cancer. The finding could not only improve prognostic and diagnostic ...
Cancer
Jan 14, 2013 |
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New technique comprehensively generates three-dimensional maps of gene expression in the brain
A research team led by Yuko Okamura-Oho and Hideo Yokota of the RIKEN Advanced Science Institute, Wako, has developed a novel technique for three-dimensional (3D) mapping of gene expression patterns onto ...
Genetics
Jan 11, 2013 |
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Potential stem cell therapy for diabetes: Study looks at differentiation of hESCs in endocrine cell progression
Type 1 and type 2 diabetes results when beta cells in the pancreas fail to produce enough insulin, the hormone that regulates blood sugar. One approach to treating diabetes is to stimulate regeneration of ...
Medical research
Jan 10, 2013 |
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Genes and obesity: Fast food isn't only culprit in expanding waistlines—DNA is also to blame
Researchers at UCLA say it's not just what you eat that makes those pants tighter—it's also genetics. In a new study, scientists discovered that body-fat responses to a typical fast-food diet are determined in large part ...
Medical research
Jan 08, 2013 |
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