Massachusetts General Hospital (MGH) investigators may have uncovered a novel mechanism behind the ability of the diabetes drug metformin to inhibit the progression of pancreatic cancer. In their report that has been published ...
Jan 14, 2016
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Interactions between an animal cell and its environment, a fibrous network called the extracellular matrix, play a critical role in cell function, including growth and migration. But less understood is the mechanical force ...
Nov 22, 2016
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Breast cancer cells ingest and consume the matrix surrounding them to overcome starvation, according to a new study published January 16 in the open access journal PLOS Biology, by Elena Rainero of the University of Sheffield, ...
Jan 16, 2024
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Scientists have engineered a synthetic biodegradable foam that can suppress inflammation, promote blood vessel growth and support the rapid healing of chronic skin wounds, an innovation that may one day improve treatment ...
The use of ciprofloxacin and other antibiotics of the class of fluoroquinolones may be associated with disruption of the normal functions of connective tissue, including tendon rupture, tendonitis and retinal detachment. ...
Jul 25, 2018
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A recent study from Uppsala University has found that genetic factors influence whether people store fat around the trunk or in other parts of your body, and that this effect is predominant in women and much lower in men. ...
Jan 21, 2019
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We may have been taught that milk does a body good, but when it comes to the ability of our tendons and ligaments to withstand the stresses of walking, running and injury, Secreted Protein Acidic and Rich in Cysteine (SPARC) ...
To make new memories, our brain cells first must find one another. Small protrusions that bud out from the ends of neurons' long, branching tentacles dock neurons together so they can talk. These ports of cellular chatter—called ...
Jul 6, 2020
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Cartilage is a fascinating substance. It coats the ends of our bones, allowing them to glide by one another at joints like our elbows and our knees. The surface it creates is about five times more slippery than ice on ice.
Mar 15, 2022
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Rice University bioengineers are fabricating and testing tunable electrospun scaffolds completely derived from decellularized skeletal muscle to promote the regeneration of injured skeletal muscle.
May 14, 2021
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In biology, the extracellular matrix (ECM) is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. The extracellular matrix is the defining feature of connective tissue in animals.
Extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.
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