Fibroblasts reprogrammed into functioning heart cells in mice
(HealthDay) -- Cells that normally form scar tissue after a heart attack can be reprogrammed into functional heart cells in mice, according to an experimental study published online April 18 in Nature.
Medical research
Apr 23, 2012 |
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Recapitulation of the entire hepatitis C virus life in engineered mouse cell lines
A US study presented today at The International Liver CongressTM 2012 demonstrates that the entire HCV lifecycle can be recapitulated in murine cells, implying that HCV permissive mouse models could soon be developed.
Diseases, Conditions, Syndromes
Apr 19, 2012 |
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Transforming scar tissue into beating hearts: The next instalment
The latest research developments to reprogram scar tissue resulting from myocardial infarction (MI) into viable heart muscle cells, were presented at the Frontiers in CardioVascular Biology (FCVB) 2012 meeting, held 30 March ...
Cardiology
Apr 01, 2012 |
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Fibroblasts contribute to melanoma tumor growth: study
Fibroblasts, cells that play a role in the structural framework of tissues, play an apparent role in melanoma tumor growth. Fibroblasts also contribute to melanoma drug resistance and may also facilitate the "flare" response ...
Cancer
Jan 05, 2012 |
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New clues to human deafness found in mice
Providing clues to deafness, researchers at Washington University School of Medicine in St. Louis have identified a gene that is required for proper development of the mouse inner ear.
Genetics
Jan 03, 2012 |
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Lab-made skin cells will aid transplantation, cancer, drug discovery research
The pigmented cells called melanocytes aren't just for making freckles and tans. Melanocytes absorb ultraviolet light, protecting the skin from the harmful effects of the sun. They also are the cells that ...
Medical research
Oct 26, 2011 |
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Scientists turns liver cells directly into neurons with new technique
(Medical Xpress) -- Fully mature liver cells from laboratory mice have been transformed directly into functional neurons by researchers at the Stanford University School of Medicine. The switch was accomplished with the introduction ...
Medical research
Oct 07, 2011 |
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Study first to link mitochondrial dysfunction and alpha-Synuclein multiplication in human fibroblasts
A new study in the Journal of Parkinson's Disease shows for the first time the effects of α-Synuclein (α-syn) gene multiplication on mitochondrial function and susceptibility to oxidative stress in human tissue ...
Diseases, Conditions, Syndromes
Oct 06, 2011 |
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Cancer drug may also work for scleroderma
A drug used to treat cancer may also be effective in diseases that cause scarring of the internal organs or skin, such as pulmonary fibrosis or scleroderma.
Medications
Sep 22, 2011 |
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Leukemia drug reverses tamoxifen-resistance in breast cancer cells
Taking a leukemia chemotherapy drug may help breast cancer patients who don't respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests. ...
Cancer
Aug 01, 2011 |
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Mice with human livers make pharmaceutical testing more accurate
(Medical Xpress) -- In a new report published in the Proceedings of the National Academy of Sciences, a team of researchers reveal a new miniature artificial human liver that can be implanted into mice to bet ...
Medical research
Jul 12, 2011 |
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Pig stem cell transplants: The key to future research into retina treatment
A team of American and Chinese scientists studying the role of stem cells in repairing damaged retina tissue have found that pigs represent an effective proxy species to research treatments for humans. The study, published ...
Medical research
Apr 13, 2011 |
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