The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue.
Dec 19, 2019
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Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix. Until ...
Nov 27, 2019
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In cell and mouse models, Mayo Clinic researchers and collaborators have identified a way to slow and reverse the process of uncontrolled internal scarring, called fibrosis.
Oct 30, 2019
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Most cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be effectively targeted with drugs that inhibit the activity of rogue cancer-promoting ...
Oct 16, 2019
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A group of researchers at Baylor College of Medicine, the Texas Heart Institute and the University of Texas Health Science Center at Houston reveals today in the journal Genes & Development new insights into the recently ...
Sep 25, 2019
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CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease. In a first-of-its-kind ...
Sep 11, 2019
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An international team of researchers has revealed how aggressive pancreatic cancer cells change their environment to enable easy passage to other parts of the body (or metastasis) - the main cause of pancreatic cancer related ...
Aug 12, 2019
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Following tissue injury, fibroblast cells activate, divide and play key roles in both tissue repair and pathological scarring—fibrosis—that can drive organ failure.
Aug 9, 2019
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What can a family of rare inherited disorders teach scientists about more common health problems like fibrosis? Plenty, based on research led by St. Jude Children's Research Hospital scientists that appears today in the journal ...
Jul 17, 2019
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Research led by the University of Birmingham has found re-purposing already existing drugs or combining therapies could be used to treat patients who have difficult to treat autoimmune diseases.
Jun 17, 2019
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