Diseases, Conditions, Syndromes

Another tantalizing step closer to a universal flu vaccine

Development of a universal flu vaccine has been a long-sought goal, and as flu scientists begin to see light at the end of a decades-long tunnel, encouraging data have emerged on an experimental shot. It appears effective ...

Diseases, Conditions, Syndromes

Four-in-one antibody used to fight flu shows promise in mice

A large international team of researchers has developed a four-in-one antibody approach to fighting influenza infections. In their paper published in the journal Science, the group describes the development of the antibody ...

Diseases, Conditions, Syndromes

Flu virus in pigs shows worrisome pandemic profile, study finds

Tests on the most common type of influenza found in Chinese pigs reveal that it has the potential to transmit easily in humans, posing a pandemic threat similar to the virus that triggered a pandemic in 2009 after jumping ...

Diseases, Conditions, Syndromes

Mystery of the pandemic flu virus of 1918 solved

A study led by Michael Worobey at the University of Arizona in Tucson provides the most conclusive answers yet to two of the world's foremost biomedical mysteries of the past century: the origin of the 1918 pandemic flu virus ...

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Orthomyxoviridae

Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus

The Orthomyxoviridae (orthos, Greek for "straight"; myxa, Greek for "mucus") are a family of RNA viruses that includes five genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus and Thogotovirus. The first three genera contain viruses that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as mosquitoes and sea lice.

The three genera of Influenzavirus, which are identified by antigenic differences in their nucleoprotein and matrix protein infect vertebrates as follows:

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