News tagged with fusion proteins
Fusion and cell death in the development of skeletal muscle
(Medical Xpress)—Membrane fusion is a highly regulated event, both inside cells, and between them. From the moment a sperm first fuses with an egg, subsequent developmental events depend upon its proper ...
Medical research
Apr 26, 2013 |
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Researchers identify new strategy for interfering with potent cancer-causing gene
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...
Cancer
Feb 11, 2013 |
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Fusion gene contributes to glioblastoma progression
Fusion genes are common chromosomal aberrations in many cancers, and can be used as prognostic markers and drug targets in clinical practice.
Cancer
Jan 09, 2013 |
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Study uncovers details of early stages in muscle formation and regeneration
(Medical Xpress)—Researchers at the National Institutes of Health have identified proteins that allow muscle cells in mice to form from the fusion of the early stage cells that give rise to the muscle cells.
Medical research
Jan 09, 2013 |
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rhBMP-2 linked to increased rate of retrograde ejaculation
(HealthDay)—For patients with lumbar spondylosis or spondylolisthesis of the lowest lumbar levels who undergo open anterior lumbar interbody fusion (ALIF), use of recombinant human bone morphogenetic protein-2 ...
Diseases, Conditions, Syndromes
Dec 29, 2012 |
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Gene sequencing project identifies abnormal gene that launches rare childhood leukemia
Research led by the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with ...
Cancer
Nov 12, 2012 |
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Not all lung cancer patients who could benefit from crizotinib are identified by FDA-approved test
Break apart a couple worm-like chromosomes and they may reconnect with mismatched tips and tails – such is the case of the EML4-ALK fusion gene that creates 2-7 percent of lung cancers. Almost exactly a year ago, the FDA ...
Cancer
Aug 28, 2012 |
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Abnormal gene product associated with prostate cancer generated by unusual mechanism
Researchers have identified a potential new pathway in prostate cancer cells by which cancer-driving gene products can be generated, according to a study published in Cancer Discovery, a journal of the American Association for Ca ...
Cancer
Jun 19, 2012 |
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Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Cancer
Jan 30, 2012 |
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Jamb and Jamc are essential proteins for the fusion of muscle cells: study
Researchers at the Wellcome Trust Sanger Institute have discovered two proteins that are essential for the fusion of muscle cells to build muscle fibres. Their discovery might help us better understand and treat illnesses ...
Medical research
Dec 13, 2011 |
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Study finds increased cancer risk with bone growth product
Spine surgery patients who got a bone growth stimulating agent as part of a clinical trial were three to five times more likely to develop cancer two to three years after being implanted with the product, according to a new ...
Cancer
Nov 04, 2011 |
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Potential leukaemia drug could be a good BET
(Medical Xpress) -- A team led by Cancer Research UK scientists in Cambridge have made a significant discovery in the lab that could lead to a new treatment for leukaemia.
Cancer
Oct 02, 2011 |
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Study offers new clues about hereditary spastic paraplegia
(Medical Xpress) -- New research from Rice University and Italy's Eugenio Medea Scientific Institute is yielding clues about hereditary spastic paraplegia (HSP), a group of inherited neurological disorders ...
Diseases, Conditions, Syndromes
Jul 08, 2011 |
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