Oncology & Cancer
Fusion gene contributes to glioblastoma progression
Fusion genes are common chromosomal aberrations in many cancers, and can be used as prognostic markers and drug targets in clinical practice.
Jan 9, 2013
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News tagged with fusion proteins
Medical research
Study uncovers details of early stages in muscle formation and regeneration
(Medical Xpress)—Researchers at the National Institutes of Health have identified proteins that allow muscle cells in mice to form from the fusion of the early stage cells that give rise to the muscle cells.
Jan 9, 2013
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Diseases, Conditions, Syndromes
rhBMP-2 linked to increased rate of retrograde ejaculation
(HealthDay)—For patients with lumbar spondylosis or spondylolisthesis of the lowest lumbar levels who undergo open anterior lumbar interbody fusion (ALIF), use of recombinant human bone morphogenetic protein-2 (rhBMP-2) ...
Dec 29, 2012
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Oncology & Cancer
Gene sequencing project identifies abnormal gene that launches rare childhood leukemia
Research led by the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with ...
Nov 12, 2012
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Oncology & Cancer
Not all lung cancer patients who could benefit from crizotinib are identified by FDA-approved test
Break apart a couple worm-like chromosomes and they may reconnect with mismatched tips and tails – such is the case of the EML4-ALK fusion gene that creates 2-7 percent of lung cancers. Almost exactly a year ago, the FDA ...
Aug 28, 2012
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Oncology & Cancer
Abnormal gene product associated with prostate cancer generated by unusual mechanism
Researchers have identified a potential new pathway in prostate cancer cells by which cancer-driving gene products can be generated, according to a study published in Cancer Discovery, a journal of the American Association ...
Jun 19, 2012
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Oncology & Cancer
Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Jan 30, 2012
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Medical research
Jamb and Jamc are essential proteins for the fusion of muscle cells: study
Researchers at the Wellcome Trust Sanger Institute have discovered two proteins that are essential for the fusion of muscle cells to build muscle fibres. Their discovery might help us better understand and treat illnesses ...
Dec 13, 2011
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Oncology & Cancer
Study finds increased cancer risk with bone growth product
Spine surgery patients who got a bone growth stimulating agent as part of a clinical trial were three to five times more likely to develop cancer two to three years after being implanted with the product, according to a new ...
Nov 4, 2011
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Oncology & Cancer
Potential leukaemia drug could be a good BET
(Medical Xpress) -- A team led by Cancer Research UK scientists in Cambridge have made a significant discovery in the lab that could lead to a new treatment for leukaemia.
Oct 2, 2011
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