Medications

Gabapentin co-use may increase risk of fatal opioid overdose

Co-prescription of the anticonvulsant gabapentin is associated with an increased risk of opioid-related death in people who are prescribed opioid painkillers, according to a new study published in PLOS Medicine.

Medications

Drug combating severe nausea in pregnancy begins clinical trial

Pregnant women with hyperemesis gravidarum, the extreme and debilitating form of morning sickness that Kate Middleton, Duchess of Cambridge, famously experienced, may find relief from a medication prescribed for seizure patients.

Surgery

Pre-op pregabalin best for pain in spinal surgery

(HealthDay)—Preoperative pregabalin is superior to either gabapentin or placebo for the relief of pain in patients undergoing lumbar discectomy, according to a study published in the March 15 issue of Spine.

Surgery

Gabapentin doesn't cut use of morphine post-knee arthroplasty

(HealthDay)—The addition of gabapentin to patient-controlled analgesia (PCA) protocol does not reduce morphine consumption, pain, or opioid-related side effects in patients undergoing total knee arthroplasty, according ...

Diseases, Conditions, Syndromes

Drugs may help relieve restless legs syndrome

(HealthDay)—People suffering from restless legs syndrome may find some relief by taking one of several drugs approved to treat the condition, a new review confirms.

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