News tagged with gene amplification


Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread

An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells ...

Cancer created May 07, 2013 | popularity not rated yet | comments 0

Blood tests can provide fuller picture of mutations in cancer than traditional biopsies do

A new blood test revealed more of the gene mutations that sustain certain digestive-tract tumors than did a DNA analysis of a traditional tumor biopsy, Dana-Farber Cancer Institute investigators will report at a special symposium ...

Cancer created Apr 07, 2013 | popularity not rated yet | comments 0

Existing drugs may help more breast cancer patients

More patients can benefit from highly effective breast cancer drugs that are already available, according to DNA sequencing studies by researchers at Washington University School of Medicine in St. Louis ...

Cancer created Dec 07, 2012 | popularity not rated yet | comments 0

Breakthrough in understanding lung cancer vulnerabilities points the way to new targeted therapy

More effective treatments for one of the deadliest forms of cancer are one step closer thanks to groundbreaking research from an international collaborative study.

Cancer created Oct 01, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Researchers show Myc protein is cancer's 'volume control'

(Medical Xpress)—A protein called Myc, commonly found at high levels inside cancer cells, fuels the disease by allowing cells to override their in-built self-destruct mechanisms, according to two new studies by US scientists.

Cancer created Oct 01, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Signaling pathway linked to inflammatory breast cancer may drive disease metastasis

Amplification of anaplastic lymphoma kinase, which has been reported in other cancers such as non-small cell lung cancers, may be a primary driver of the rapid metastasis that patients with inflammatory breast cancer experience.

Inflammatory disorders created Nov 13, 2011 | popularity not rated yet | comments 0