Oncology & Cancer

Single-nucleus RNA sequencing, droplet by droplet

Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This system enabled researchers to study the gene expression profiles of difficult-to-isolate cell types as well as cells from ...

Obstetrics & gynaecology

Lack of a hormone in pregnant mice linked to preeclampsia

(Medical Xpress)—A team of researchers from Singapore, the Netherlands and Turkey has isolated a hormone in pregnant mice that appears to be associated with preeclampsia—a pregnancy-related condition characterized by ...

Medical research

Researchers use single-cell sequencing to understand how cells age

Researchers from the European Bioinformatics Institute (EMBL-EBI), University of Cambridge, the Wellcome Trust Sanger Institute and the Cancer Research UK-Cambridge Institute (CRUK-CI) have shed light on a long-standing debate ...

Oncology & Cancer

New method offers potential for uncovering how cancer begins

At Baylor College of Medicine, scientists have developed a method that allows them to accurately determine the genes expressed in single cells. Among other applications, this technique can be useful to study how cancerous ...

Genetics

Tapping crowd-sourced data unearths a trove of depression genes

Scientists have discovered 15 genome sites - the first ever - linked to depression in people of European ancestry. Many of these regions of depression-linked genetic variation turn out to be involved in regulating gene expression ...

Immunology

Immunology meets single-cell sequencing

Research from the Single-Cell Genomics Centre on the Wellcome Genome Campus could change the way we look at gene expression and immune response. Published in Nature Methods, the new method, TraCeR, provides a powerful tool ...

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