Length matters in gene expression
A research team at Aarhus University reveals a surprising interplay between the ends of human genes: If a protein-coding gene is too short it becomes inactive! The findings also explain how some short genes have adapted to ...
Genetics
Oct 02, 2012 |
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Putting a 'HEX' on muscle regeneration
A complex genetic regulatory network mediates the regeneration of adult skeletal muscles. In this issue of the Journal of Clinical Investigation, researchers at the State University of New York Downstate Medical Center in Bro ...
Medical research
Oct 01, 2012 |
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Specific regions of the hippocampus connected to discrete steps of task mastery, study finds
(Medical Xpress)—In a study published in Nature Neuroscience, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have been linking synapse formation in the hippocampus to distinct learning steps. ...
Neuroscience
Oct 01, 2012 |
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Aggressive cancer exploits MYC oncogene to amplify global gene activity
Whitehead Institute researchers have determined the mechanism used by c-Myc to increase the expression of all active genes in cancer cells. Elevated levels of c-Myc are linked to increased rates of metastasis, disease recurrence, ...
Cancer
Sep 27, 2012 |
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Mechanism that leads to sporadic Parkinson's disease identified
Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease, the progressive movement ...
Parkinson's & Movement disorders
Sep 25, 2012 |
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Addictive properties of drug abuse may hold key to an HIV cure
A Florida State University researcher is on a mission to explore the gene-controlling effects of addictive drugs in pursuit of new HIV treatments.
HIV & AIDS
Sep 21, 2012 |
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RNA interference for human therapy
Leading scientists in the field investigated the potential of RNA interference (RNAi) technology as a therapeutic intervention for down-regulating the expression of disease-associated genes. Project deliverables ...
Medical research
Sep 20, 2012 |
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Men and women are different in terms of genetic predispositions, study shows
We are not all the same when it comes to illness. In fact, the risk of developing a disease such as diabetes or heart disease varies from one individual to another. A study led by Emmanouil Dermitzakis, Louis-Jeantet Professor ...
Genetics
Sep 20, 2012 |
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The molecular mechanisms behind the benefits of exercise
Leading a sedentary lifestyle increases risk of developing type 2 diabetes. European scientists focused on delineating the mechanisms responsible for the beneficial effects of exercise on our metabolism.
Other
Sep 20, 2012 |
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Study: Common gene mutation affects kids with autism spectrum disorders
(Medical Xpress)—Over the past decade, researchers have made great strides in identifying genes that lead to an increased risk of autism spectrum disorders (ASD), which result in a continuum of social deficits, communication ...
Autism spectrum disorders
Sep 14, 2012 |
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Wnt signaling pathway plays key role in adult nerve cell generation: study
Researchers from the University of Utah have gained new insight into the regulation of adult nerve cell generation in the hypothalamus, the part of the brain that regulates many aspects of behavior, mood, and metabolism. ...
Medical research
Sep 10, 2012 |
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Definition of lung squamous cell carcinoma genome opens doors to better, more targeted therapies
A new paper published online in Nature holds out hope that people with the second most common type of lung cancer may one day benefit from targeted therapies that have transformed treatments for other lung cancer patients.
Cancer
Sep 09, 2012 |
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Study finds how BPA affects gene expression, anxiety; Soy mitigates effects
New research led by researchers at North Carolina State University shows that exposure to the chemical bisphenol A (BPA) early in life results in high levels of anxiety by causing significant gene expression changes in a ...
Medical research
Sep 07, 2012 |
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Improving diagnosis of thyroid nodules
Thyroid nodules are thought to be present in about half of all people, but very few of these are cancerous. New research published in BioMed Central's open access journal BMC Cancer presents a set of dia ...
Cancer
Sep 06, 2012 |
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Researchers find acidic pH microenvironments in tumors aid tumor cell survival
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment. ...
Cancer
Sep 06, 2012 |
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