Weight gain and weight loss are not as simple as "calories in, calories out," given that countless factors affect body weight. Now, researchers from Japan have identified a gene that may serve as a master regulator of fat ...
Nov 27, 2023
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Researchers led by the University of Tsukuba conducted a gene expression analysis at the single-cell level on pancreatic islets from prediabetic and diabetic mouse models. Their results are published in the journal Diabetes.
Nov 21, 2023
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It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism—the intrinsic link between metabolism in immune cells and their immune function. ...
Nov 20, 2023
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Scientists at St. Jude Children's Research Hospital described the gene regulatory networks contributing to differences between subtypes of the most common childhood cancer, acute lymphoblastic leukemia (ALL). The work examined ...
Nov 20, 2023
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Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant ...
Nov 16, 2023
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The cells that make up our bodies are constantly communicating with each other, sometimes directly by physical touch. These interactions allow cells to respond to their neighbors, adapt to their surrounding environment and ...
Nov 16, 2023
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A new research paper titled "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model" has been published in Aging.
Nov 15, 2023
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Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks. This process is mediated by molecules called DNA methyltransferases. ...
Nov 15, 2023
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Pediatric rhabdomyosarcoma is a type of cancerous tumor that arises in the soft tissue, such as muscles, though the origin of one of the most aggressive subtypes is unclear.
Nov 15, 2023
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T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known ...
Nov 15, 2023
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